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Table 2 Comparison of the disease status, cognition, and resting-state magnetic resonance data of SC before and after treatment

From: Abnormalities of the Amygdala in schizophrenia: a real world study

 

SC 0−week

SC 24−week

t

p

PANSS

67.33 ± 14.339

56.41 ± 12.933

3.131

0.003*

PANSS (positive)

13.88 ± 6.294

10.38 ± 4.467

2.492

0.015*

PANSS (negative)

21.09 ± 5.719

19.59 ± 6.193

0.994

0.324

PANSS (general)

32.36 ± 7.141

26.45 ± 5.047

3.718

< 0.001*

RBANS

125.757 ± 32.939

138.093 ± 39.223

-1.346

0.183

Immediate memory (Learning)

11.35 ± 4.996

22.57 ± 6.155

-2.641

0.011*

Immediate memory (Story Memory)

6.30 ± 4.760

10.46 ± 4.925

-3.349

0.001*

Visuospatial Construction

15.42 ± 3.783

16.46 ± 3.203

-1.147

0.256

Language

12.27 ± 4.598

12.71 ± 3.463

-0.417

0.678

Attention (Digit Span)

10.91 ± 2.590

10.86 ± 2.256

0.083

0.934

Attention (Coding)

29.82 ± 11.151

32.36 ± 10.962

-0.893

0.375

Delayed memory (List Recall)

3.15 ± 2.647

4.54 ± 2.546

-2.071

0.043*

Delayed memory (List Recognition)

17.85 ± 2.476

18.54 ± 3.574

-0.883

0.381

Delayed memory (Story Recall)

3.24 ± 3.042

5.11 ± 2.936

-2.424

0.018*

Delayed memory (Figure Recall)

8.52 ± 5.357

9.43 ± 4.947

-0.687

0.495

Volume (Amygdala)

L

0.905 ± 0.104

0.900 ± 0.102

0.183

0.426

 

R

1.019 ± 0.111

0.980 ± 0.093

1.544

0.127

FALFF (Amygdala)

L

-0.073 ± 0.358

-0.086 ± 0.342

0.282

0.779

 

R

-0.211 ± 0.360

-0.145 ± 0.336

1.849

0.073

  1. PANSS: Positive and Negative Syndrome Scale; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status; FALFF: Fractional amplitude of low-frequency fluctuations; L: left; R: right. *Indicated p < 0.05; Paired-sample t-test, two-tailed.