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Table 2 Study characteristics of intervention studies

From: Religiosity and spirituality in the prevention and management of depression and anxiety in young people: a systematic review and meta-analysis

Study name & year

Country

Study design

N (INT, CONT)

Follow-up points

Study population

%F

Mean age in years (SD), range

Description of intervention

Intervention length

Comparison condition & description

Mental health outcomes

Quality rating

Anxiety

Depression

Anastasi [66], 2008

USA

Quasi-experimental

30 (12,18)

post

College students

NR

NR

Recitation of the Rosary in a campus chapel

30 min

Watched 30 min video of religious content

STAI: ↓ (State), NS (Trait)

NA

Moderate risk of bias

Armento [67], 2012

USA

RCT

50 (25,25)

1-month

Undergraduate students with > 14 BDI-II score

62%F

20(2.75)

Single session of modified Behavioral Activation treatment and post-session activation completing religious activities

60 min + 2 week activation

Single session of supportive therapy

BAI: ↓ (Somatic)

STAI: ↓ (Trait)

(Maintained at follow-up)

BDI-II: ↓ (Maintained at follow-up)

Moderate risk of bias

Charkabi [68], 2014*

Iran

RCT

60 (30,30)

post

Secondary school students

NR

14.93(INT)

14.82(CONT)

Spiritual intelligence training to solve problems in everyday life

7-weekly sessions

No intervention

SCL-90-R: NS (INT only)

SCL-90-R: NS (INT only)

High risk of bias

Chen [27, 69], 2005

USA

RCT

177 (90,87)

1-month

College students

59%F

19.5(2.48)

Written exercise on an experience of trauma from a religious or spiritual perspective

3 writing sessions over one week

Written exercise on an experience of trauma

IES-R: NS (PTSD symptoms)

NA

High risk of bias

Chen [70], 2009

USA

RCT

Total = 215, Religious writing = 90

Conventional trauma writing = 87

CONT = 38

1-month

College students

57%F

19.3 (2.36)

Written exercise on an experience of trauma from a religious or spiritual perspective

3 writing sessions over one week

Written exercise on an experience of trauma (CTW)

Written exercise on a trivial experience (CONT)

NA

CES-D: NS

High risk of bias

Chen [71], 2018

Taiwan

RCT

105 (52,53)

1-month

College students

54%F

20.7(3.47)

Written exercise on an experience of trauma from a religious or spiritual perspective

3 writing sessions over one week

Written exercise on an experience of trauma

IES-R: NS

(PTSD symptoms)

NA

High risk of bias

Dami [72], 2019

Indonesia

Quasi-experimental

64 (32,32)

post, 5-weeks

Christian Religious Education Study Program students

69%F

18–30

Group counselling with a spiritual approach with sessions based on spiritual intelligence book and an emphasis on biblical principles

7 60-min sessions

NR

DASS-21 anxiety sub-scale: ↓

DASS-21 depression sub-scale: ↓

Moderate risk of bias

Ebrahimi [73], 2015

Iran

Quasi-experimental

40 (20,20)

Post

Male high school students

0%F

16.48(1.10)

Group cognitive-behavioural therapy with spiritual intelligence training component

8 sessions

NR

DASS-42 anxiety sub-scale: ↓

DASS-42 depression sub-scale: ↓

Moderate risk of bias

Hajra [74], 2021

Pakistan

Pre-post

60

Low religiosity: 30

High religiosity: 30

Post

University students with mild to moderate DASS-21 scores and low/high religiosity levels

61.7%F

18–30

Islamic art therapy involving completing patterns from an Islamic adult colouring book and free-hand calligraphy

14 daily 35-45min sessions

NA

DASS-21 anxiety sub-scale: ↓

DASS-21 depression sub-scale: ↓

Moderate risk of bias

Heidari [75], 2019

Iran

Quasi-experimental

60 (30,30)

Post

Individuals admitted to hospital for a suicide attempt

62%F

Predominantly emerging adults (80%)

Spiritual care counselling

8 sessions

NR

NA

BDI-II: ↓

High risk of bias

Kadafi [76], 2021

Indon esia

Quasi-experimental

14 (7,7)

Post

High school students with high anxiety

64%F

16–18

Islamic counselling sessions

3 40-min sessions

Individual counselling including Covid-19 information and advice

CAS: ↓

NA

Moderate risk of bias

Khaki [77], 2021

Iran

Quasi-experimental

152 (76,76)

Post

Female university students

100%F

NR

Religious and spiritual teachings

15 sessions

NR

GHQ-28 anxiety component: ↓

GHQ-28 depression component: ↓

High risk of bias

Khubalkar [78], 2009

India

Pre-post

12

Post

University graduate psychology students

50%F

21.58(NR), 21–23

Single integral meditation session

20 min

NA

STAI: ↓ (State), ↓ (Trait)

NA

Moderate risk of bias

Klawonn [79], 2019

USA

Quasi-experimental

21

Post

Graduate healthcare students with <  = 16 on BDI

67%F

25(4), 23–29

Seminars on meditation with reading, breathing techniques, education on the kosha model, mindful movement/modified asana, and supine guided meditation

5 weekly 60-min seminars

5-week baseline control period

BAI: ↓

BDI: ↓

Moderate risk of bias

Lolla [80], 2018

India

Pre-post

52

Post

College students

NR

17–20

Listening to mantras at home

40-min at least four days per week over 60 days

NA

PGWBI anxiety dimension: ↓

PANAS negative affect subscale: ↓

PGWBI depressed mood dimension: NS

Moderate risk of bias

Maddix [81], 2018

USA

Quasi-experimental

60 (38,22)

Post

Undergraduate university students

NR

23(NR), 17–42

Spiritual disciplines taught and practiced in a history of spiritual practices and neuroscience course

7 weekly sessions

Not enrolled in course

STAI: NS (State and trait)

BDI: NS

Moderate risk of bias

Mastropieri [82], 2015

USA

Pre-post

13

Post

Emerging adult men from a homeless shelter transitional living program

0%F

22.38 (1.03), 20.27–23.38

Group psychotherapy with spiritual visualization

16 weekly 90-min sessions

NA

GAD-7: NS

PHQ-12: ↓

Low risk of bias

GHQ-12: ↓ (Psychological distress)

Pandya [83], 2021

India, Kenya, Nepal, South Africa

RCT

96 (48,48)

Post

Deaf and hard-of-hearing university students

37.5%F

INT: 21.48 (2.63)

CONT: 21.34 (2.08)

Online spiritual counselling program

50 weekly 1-h sessions

Online relaxation sessions

GAD-7: ↓

NA

Low risk of bias

Penberthy [84], 2017

USA

Pre-post

205

Post

Undergraduate college students

68.1%F

20.7(1.6), 18–36

Buddhism Meditation and Modernity course covering knowledge and practice

13 bi-weekly lectures

NA

STAI: ↓

PANAS negative affect sub-scale: NS

Low risk of bias

Rickhi [85], 2015

Canada

RCT

62 (31,31)

Post, 16-weeks, 24-weeks

Adolescents and young adults with mild-to-moderate MDD

71%F

12–24

Online modules on spiritually informed principles (e.g., forgiveness, gratitude, compassion)

8 2-3h weekly modules

Waitlist

NA

CES-D (adolescents): ↓

HAMD (young adults): ↓

Low risk of bias

Safara [86], 2012

India, Iran

Quasi-experimental

64 (32,32, 32)

Post

Iranian female university students residing in Iran and India

100%F

18–45

Spiritual therapy

5 bi-weekly sessions

Cognitive therapy (CT)

No intervention control (CONT)

NA

BDI: ↓ (INT vs CT; INT vs CONT)

Moderate risk of bias

Scott Richards [87], 2006

USA

RCT

122, (43, C: 35, ES: 44)

Post

Women receiving in-patient eating disorder treatment

100%F

21.2(6.6), 13–52

Read and participated in group discussion on Spiritual Renewal: A Journey of Faith and Healing, a self-help workbook on non-denominational spiritual readings and Judeo-Christian education materials

Reading + weekly 60-min group

Cognitive group: Read and participated in weekly group discussion on a CBT self-help workbook and attended

Emotional support group: Weekly “open-topic” support group

OQ-45 anxiety subscale: ↓

OQ-45 depression subscale: ↓

High risk of bias

Singh

2021 [88], (Study 1)

India

Pre-post

42

Post, 21-days

Undergraduate college students

14.2%F

21.17(1.53), 19–27

Multi-component wellbeing program covering topics on mindfulness and meditation and videos of Indian spiritual leaders imparting psychological messages

14 25–40 min sessions

NA

DASS-21: ↓ (post), NS (follow-up)

Low risk of bias

Singh 2021 [88], (Study 2)

India

Pre-post

308

Post

Undergraduate college students

31.8%F

19.26(1.49), 18–26

Multi-component wellbeing program covering topics on mindfulness and meditation and videos of Indian spiritual leaders imparting psychological messages

14 25–40 min sessions

NA

DASS-21: NS

Low risk of bias

Singh 2021 [88], (Study 3)

India

Pre-post

112

Post

College freshman

28.6%F

18.24 (0.60), 18–20

Multi-component wellbeing program covering topics on mindfulness and meditation and videos of Indian spiritual leaders imparting psychological messages

NR

NA

DASS-21: NS

Moderate risk of bias

Smith [89], 2011*

USA

Quasi-experimental

81 (INT: 33, exercise yoga: 15, cont: 32)

Post

Undergraduate students with mild-to-moderate depression, anxiety and stress

50.5%F

21.15 (4.15)

Hatha yoga with a meditation based on one of the yamas or niyamas of yogic philosophy

Bi-weekly 60-min sessions for 7 weeks

Yoga-as-exercise: Hatha yoga only

No intervention control

DASS anxiety sub-scale: ↓ (INT only)

DASS depression sub-scale: ↓(INT only)

Low risk of bias

Vazifeh Doust [90], 2020*

Iran

RCT

40 (20,20)

Post

Children undergoing hospital treatment

52.5%F

NR

Training program on spiritual care covering topics on trust, coping, prayer, thanksgiving, and patience

Five 45–60 min sessions over 4 weeks

Disease and care in chemotherapy pamphlets

MASC: ↓ (INT only)

NA

High risk of bias

Wachholtz [91], 2008

USA

RCT

92 (spiritual med: 25, Internal secular med: 22, External secular med: 23, Relaxation: 22)

Post

Meditation naïve psychology university students meeting criteria for vascular headache

90.4%F

19.1 (1.10)

Spiritual meditation involving aloud soft repetition of one of four spiritual meditation phrases (e.g., “God is peace”) to help with focus

20-min daily for one month

(1) Internal secular meditation, (2) External secular meditation, (3) Progressive muscle relaxation

STAI: ↓ (trait)

CES-D: NS

PANAS negative affect sub-scale: ↓

Moderate risk of bias

Wachholtz [91], 2005

USA

RCT

84 (spiritual med: 25, Secular med: 21, Relaxation: 22)

2-weeks

University students

68%F

19.1 (1.03)

Spiritual meditation involving aloud soft repetition of one of four spiritual meditation phrases (e.g., “God is peace”) to help with focus

20-min daily for two weeks

(1) Secular meditation, (2) Relaxation

STAI: ↓

PANAS negative affect sub-scale: NS

High risk of bias

  1. * Quasi-experimental or RCT studies that reported within group differences only, BAI Beck Anxiety Inventory, BDI Beck Depression Inventory, CAS Coronavirus Anxiety Scale, CES-D Center for Epidemiologic Studies Depression Scale, DASS Depression Anxiety Stress Scales, GAD-7 General Anxiety Disorder-7, GHQ General Health Questionnaire, HAMD Hamilton Depression Rating Scale (HAM-D), IES-R The Impact of Event Scale – Revised, OQ-45 Outcome Questionnaire 45, PANAS-N Positive and Negative Affect Schedule, PGWBI Psychological General Wellbeing Index, PHQ-12 Patient Health Questionnaire, SCL-90-R Symptom Checklist-90-Revised, STAI The State-Trait Anxiety Inventory, ↓ Significant reduction (p < .05) in anxiety or depressive symptoms, med- meditation, NS = no significant different in anxiety or depressive symptoms