Joint effects of depressive status and body mass index on the risk of incident hypertension in aging population: evidence from a nationwide population-based cohort study

Table 2 Associations and interactions between depressive status and BMI of hypertension incidence^a

	Multiplicative interaction	Additive interaction
	HR (95%CI)	RERI (95%CI)	AP (95%CI)	S(95%CI)
Model DES
BMI
overweight	1.68(1.29,2.19)	1.13(0.17,2.09)	0.43(0.26,0.59)	3..18(2.10,4.82)
obesity	1.94(1.15,3.26)	2.28(-0.37,4.94)	0.52(0.26,0.78)	3.08(1.56,6.07)
Model Depression
BMI
overweight	1.60(1.19,2.17)	1.08(0.03,2.14)	0.41(0.21,0.60)	2.88(1.81,4.57)
obesity	2.79(1.68,4.63)	4.47(0.28,8.66)	0.67(0.50,0.85)	4.86(2.66,8.86)

BMI Body mass index, DES Depressive symptoms, RERI Relative excess risk due to interaction, AP Attributable proportion, S Synergy index
^aModels were adjusted for age, sex, dyslipidaemia, diabetes, nephropathy, history of smoking, history of drinking

ISSN: 1471-244X