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Table 3 GRADE scoring: certainty of the evidence

From: Crisis and acute mental health care for people who have been given a diagnosis of a ‘personality disorder’: a systematic review

Model

Outcomes assessed

Comparison group

Direction of effect found

Grade score

Hospital admission (no comparator models, all studies reporting changes over time)

Symptomatic improvement over time (range of measures including HoNOS)

No, change over time only

Improvement in symptoms scores

Very low

Improvement in adaptive functioning over time

No, change over time only

Improvement in adaptive functioning

Very low

The brief admission model of hospital admission

Service use (days in hospital)

Treatment as usual

No effect of the intervention

Moderate    

Symptomatic improvement (range of measures)

No, change over time only

Improvement in symptoms scores

Very low

NSSI and suicide attempts

Treatment as usual

No effect of the intervention

   Low

Health Related QoL

No, change over time only

Improvement in QoL

Very low

Therapeutic alliance

No, change over time only

Improvement in therapeutic alliance

Very low

Crisis teams

CGI

No, change over time only

Improvement in CGI scores

Very low

Acute day units

Symptomatic improvement (range of measures)

Telehealth version of ADU (1 study) Otherwise change over time only

Improvement in symptom scores

Very low

Social participation

No, change over time only

Improvement in social participation

Very low

Patient Satisfaction

Telehealth version of ADU

Higher satisfaction with in person versus telehealth ADU

Very low

Psychotherapies or psychosocial interventions: Outpatient based

Hospitalisation

TAU or TAU plus waitlist for psychological treatment

Reduction in % hospitalised, increased time to hospitalisation, reduction in number of admissions and bed days

Moderate    

Suicide attempt or suicide

TAU

Reduction in number of suicidal relapses and time to relapse

Moderate    

Symptomatic improvement

No, change over time only

Improvement in symptoms scores

Very low

Psychotherapies or psychosocial interventions: Based in emergency departments, general hospitals or psychiatric emergency services

Repeat suicide attempt

Historical TAU

Reduction in % of participants attempting suicide

Very low

Hospitalisation

Historical TAU

Increased time to readmission and reduced days of hospitalisation

Very low

Symptomatic improvement (range of measures)

No, change over time only

Improvement in symptoms scores

Very low

Psychotherapies or psychosocial interventions: groups delivered in inpatient services

Symptomatic improvement (range of measures)

‘Living well group’

No effect of the intervention

   Low

Self-harm (including both suicide attempt and non-suicidal self-harm (NSSH)

No, change over time only

Reduction in frequency of self harm

Very low

Mother and Baby Units

GAF

No, change over time only

Reduction in score from discharge to 3 months

Very low

Joint crisis planning

Symptomatic improvement

Treatment as usual

No effect of the intervention

   Low

NSSI

No effect of the intervention

   Low

Early Intervention Service

Symptomatic improvement

Treatment as usual (hospital-based services)

Greater improvement in the treatment as usual group

   Low

Social functioning

Greater improvement in the treatment as usual group

   Low

  1. ADU- acute day unit, CGI clinical global impression, GAF Global Assessment of Function, GRADE GRADE Grading of Recommendations, Assessment, Development, and Evaluations, HoNOS Health of the Nation Outcome Scales, QoL quality of life, NSSH Non-suicidal self-harm, NSSI Non-suicidal self-injury, TAU Treatment as Usual