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Table 8 Validity (AUC, sensitivity, specificity) for NRG-1 (ng/ml) to discriminate between pre-LSG obese subjects with (mild /moderate /severe) depression (n = 53) and non-depressed subjects (n = 55)

From: Is neuregulin-1 (NRG-1) a potential blood biomarker linking depression to obesity? A case-control study

 

AUC

P

95% C.I

Cut offa

Sensitivity

Specificity

PPV

NPV

NRG-1 (ng/ml)

0.838

< 0.001*

0.760–0.916

≤ 3.5

92.45

69.09

74.2

90.5

  1. AUC Area Under a Curve, p value Probability value, CI Confidence Intervals, NPV Negative predictive value, PPV Positive predictive value
  2. *Statistically significant at p ≤ 0.05
  3. aCut off was choose according to Youden index
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BMC Psychiatry

ISSN: 1471-244X

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