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Table 3 MiRNAs statistically significant for Conner’s hyperactivity or inattention score

From: Blood miRNA levels associated with ADHD traits in children across six European birth cohorts

 

miRNA

log2FC

95% CI

Adj. p value

Hyperactivity

hsa-miR-144-3p

-0.0361

 ± 0.0220

0.0240

hsa-miR-19a-3pa

-0.0278

 ± 0.0155

0.0148

hsa-miR-142-3pa

-0.0268

 ± 0.0152

0.0154

hsa-miR-101-3pa

-0.0252

 ± 0.0130

0.0148

hsa-miR-29c-3p

-0.0251

 ± 0.0139

0.0148

hsa-miR-29b-3p

-0.0244

 ± 0.0133

0.0148

hsa-miR-29a-3p

-0.0222

 ± 0.0135

0.0240

hsa-miR-19b-3pa

-0.0211

 ± 0.0133

0.0299

hsa-miR-148b-3pa

-0.0192

 ± 0.0107

0.0148

hsa-miR-30e-5pa

-0.0190

 ± 0.0105

0.0148

hsa-miR-130a-3pa

-0.0185

 ± 0.0110

0.0224

hsa-miR-150-5pa

-0.0182

 ± 0.0123

0.0423

hsa-let-7i-5pb

-0.0175

 ± 0.0096

0.0148

hsa-miR-181b-5p

-0.0168

 ± 0.0094

0.0148

hsa-miR-186-5p

-0.0164

 ± 0.0091

0.0148

hsa-miR-146b-5p

-0.0161

 ± 0.0102

0.0299

hsa-miR-106b-5pa

-0.0157

 ± 0.0101

0.0300

hsa-miR-942-5pa

-0.0156

 ± 0.0076

0.0148

hsa-miR-107a

-0.0149

 ± 0.0085

0.0161

hsa-miR-27a-3pa

-0.0144

 ± 0.0093

0.0300

hsa-miR-140-3pa

-0.0136

 ± 0.0081

0.0225

hsa-miR-181a-5p

-0.0135

 ± 0.0087

0.0300

hsa-miR-24-3pa

-0.0127

 ± 0.0083

0.0322

hsa-miR-92a-3pa

-0.0127

 ± 0.0076

0.0225

hsa-let-7c-5pb

-0.0127

 ± 0.0081

0.0300

hsa-miR-103a-3pb

-0.0123

 ± 0.0084

0.0461

hsa-miR-342-5p

-0.0121

 ± 0.0083

0.0458

hsa-miR-324-5p

-0.0119

 ± 0.0075

0.0299

hsa-miR-378i

-0.0112

 ± 0.0074

0.0354

Inattention

hsa-miR-4257

-0.0159

 ± 0.0080

0.0282

hsa-miR-4443

0.0197

 ± 0.0103

0.0282

hsa-miR-3180-3p

0.0198

 ± 0.0107

0.0287

  1. Significance at FDR < .05. Table sorted by log2FC. log2FC, log2 fold-change defined as change in expression per unit of increase in the predictor variable; 95% CI 95% confidence interval for log2FC, Adj. p value P value adjusted by FDR correction
  2. a miRNAs associated with ADHD in previous literature
  3. b miRNAs belonging to miRNA-families associated with ADHD in previous literature