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Table 1 Summary of characteristics of studies in the current meta-analysis

From: A meta-analysis on the therapeutic efficacy of repetitive transcranial magnetic stimulation for cognitive functions in attention-deficit/hyperactivity disorders

Study (year)

Diagnosis (Criteria)

Design

Comparison

N

Duration (weeks)

Frequency (Hz)

Intensity of stimulation

Number of sessions

Outcome

Medications

Mean age (years)

Female (%)

Country

Bleich-Cohen M (2021) [18]

ADHD (DSM-5)

RCT

rTMS: rPFC

24

3

18

120% of RMT

15

Sustain attention: Mindstreams attention Working memory: Mindstreams memory Processing speed: Mindstreams information Processing Executive control: Mindstreams Executive function

Allowed only SSRI and SNRI Not allowed neuroleptics or psychostimulant

35.1 (18–60)

34.7

Israel

rTMS: lPFC

22

Sham

16

Alyagon U (2020) [20]

ADHD(DSM-5)

RCT

rTMS: rPFC

15

3

18

120% of RMT

15

Sustain attention: Mindstreams attention Working memory: Mindstreams memory Processing speed: Mindstreams information Processing Executive control: Mindstreams Executive function

Not allowed psychostimulant

27.1 (21–64)

82.76

Israel

Sham

14

Cao P (2018) [30]

ADHD (DSM-5)

RCT

rTMS: rPFC + ATX

21

6

10

100% of RMT

30

Sustain attention: CPT Working memory: Digit span Processing speed: WISC – coding Executive control: IGT

All participants used atomoxetine

8.53 (6–13)

15.63

China

ATX only

19

Paz Y (2018) [19]

ADHD (DSM-5)

RCT

rTMS: bil.PFC

12

4

18

120% of RMT

20

Sustain attention: T.O.V.A

Not allowed any neuropsychiatric medications

31.6 (≥ 18)

46.15

Israel

Sham

14

Loughead J NCT03663179

ADHD (SCID-5)

RCT

rTMS: lPFC

18

4

10

120% of RMT

20

Sustain attention: CPT

N/A

34.4 (18–65)

33

USA

Sham

14

  1. Abbreviations: ADHD Attention-deficit/hyperactivity disorder, ATX Atomoxetine, bil.PFC Bilateral prefrontal cortex, CPT Continuous performance test, DSM-5 Diagnostic and statistical manual of mental disorders fifth edition, IGT Iowa Gambling Task, lPFC left prefrontal cortex, N Number, RCT Randomized controlled trial, RMT Rest motor threshold, rPFC Right prefrontal cortex, rtms repetitive transcranial magnetic stimulation, scid-5 the Structured Clinical Interview for DSM-5 SNRI serotonin and norepinephrine reuptake inhibitors, SSRI Serotonin reuptake inhibitor, T.O.V.A Test of Variables of Attention, WISC Wechsler Intelligence Scale for Children