Table 1 Inclusion and exclusion criteria for patients
Inclusion Criteria | Exclusion Criteria |
|---|---|
• Diagnosis of major depression and/or dysthymia (based on Structural Clinical Interview-SCID) for at least 12 months • BDI-2 > 17 • QIDS > 9 • CTQ: at least trauma at one of the subscales • Age: 21–60 years • Sufficient knowledge of local language • Informed consent to study protocol • Need to be free of anti-depressant, anti-anxiety, and antipsychotic medication for at least 3 weeks before baseline assessment and be deemed stable by their treating clinician at the study onset | • Current or past psychotic symptoms in the last 3 years, schizoaffective, schizophrenic, or bipolar affective disorder • Substance dependence current or during the last three years • Dementia • Borderline, schizotypal, or antisocial personality disorder • Acute suicidality • Reduced intellectual capacity • Serious physical illness that strongly affects the depression or is causal for the depression • Concurrent psychotherapy • Technical exclusion criteria for MRI (metallic tattoos, pacemakers, or other metal parts in the body etc., according to special guidelines of the local MRI team) |