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Table 4 Association of CLOCK-PRS and chronotype interactions with clustering of HRB in adolescents

From: Role of polygenic risk scores in the association between chronotype and health risk behaviors

Variables

Model 1

 

Model 2

Model 3

Low

High

Low

High

Low

High

PRS + chronotype

       

High PRS+eveningness

1.0

3.50(0.56,22.03)

 

1.0

3.72(0.58,23.70)

1.0

4.02(0.61,26.51)

High PRS+intermidiate

1.0

1.84(0.46,7.44)

 

1.0

1.75(0.43,7.11)

1.0

1.69(0.40,7.04)

High PRS+morningness

1.0

1.52(0.32,7.16)

 

1.0

1.44(0.30,6.80)

1.0

1.69(0.34,8.35)

Medium PRS+eveningness

1.0

  

1.0

 

1.0

 

Medium PRS+intermidiate

1.0

1.62(0.39,6.62)

 

1.0

1.66(0.40,6.82)

1.0

1.72(0.40,7.35)

Medium PRS+morningness

1.0

1.47(0.29,7.45)

 

1.0

1.51(0.30,7.69)

1.0

1.65(0.31,8.77)

Low PRS+eveningness

1.0

5.25(1.05,26.20)*

 

1.0

5.57(1.10,28.20)*

1.0

5.66(1.06,30.22)*

Low PRS+intermidiate

1.0

0.93(0.21,4.10)

 

1.0

1.06(0.24,4.70)

1.0

1.12(0.25,5.15)

Low PRS+morningness

1.0

1.0

 

1.0

1.0

1.0

1.0

  1. Model 1 : crude model ; Model 2: Adjusted for gender, age; Model 2: Adjusted for gender, age, educational level of parents, family residence, only child, self-rated family financial status, number of friends and learning burden