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Table 3 Brain area differences in functional connectivity between patients with AUD and HC (FWE corrected)

From: Alterations of brain activity in patients with alcohol use disorder: a resting-state fMRI study

Seed area

Peak MNI coordinate region

Side

Cluster Size

BA

Peak MNI coordinates

T value

X

Y

Z

Seed 1

        
 

Inferior temporal gyrus

R

92

-

48

-54

-21

-4.34

 

Middle temporal gyrus

R

98

21

66

-45

-3

-4.83

 

Dorsolateral superior frontal gyrus

L

147

6

-21

15

57

-5.38

Seed 2

        
 

Inferior parietal lobule

R

800

40

42

-57

45

-6.12

 

Inferior parietal lobule

L

367

40

-54

-45

48

-6.19

Seed 3

        
 

Precuneus

L

115

3

-12

-39

66

-4.63

 

Lingual gyrus

L

163

17

-21

-96

-18

-5.14

 

Cerebellum_Crus1/

Inferior temporal gyrus/

Inferior occipital gyrus

R

189

-

54

-57

-30

-4.27

 

Superior parietal gyrus

R

457

-

30

-48

39

-5.49

 

inferior parietal lobule

L

220

40

-42

-48

36

-5.76

  1. Seed 1, left precentral gyrus (-45,0,30)
  2. Seed 2, left inferior parietal lobule (-42,-48,36)
  3. Seed 3, left inferior parietal lobule (-54,-45,51)
  4. AUD, alcohol use disorder; HC, healthy controls; MNI, Montreal Neurological Institute; BA, Brodmann area; L, left; and R, right