Table 1 Endorsement of specific symptoms of DSM criteria for major depression, melancholia, and atypical specifiers in patients with MDD, MDD with melancholia features, and MDD with atypical features, as determined by the AUDADIS-IV
From: Methods for quantifying the heterogeneity of psychopathology
AUDADIS-MDE | AUDADIS-Mel | AUDADIS-Aty | ||||
|---|---|---|---|---|---|---|
Symptom | % | (n) | % | (n) | % | (n) |
Sad mood | 94.97 | 5460 | 95.51 | 2277 | 94.12 | 769 |
Anhedonia | 87.60 | 5036 | 100 | 2384 | 85.68 | 700 |
Appetite/weight decreasea | 60.08 | 3454 | 86.45 | 2061 | 17.87 | 146 |
Appetite/weight increaseb | 36.42 | 2094 | 29.07 | 693 | 100 | 817 |
Insomnia sleep onset | 69.42 | 3991 | 84.02 | 2003 | 46.88 | 383 |
Early morning awakening | 54.90 | 3156 | 82.38 | 1964 | 21.67 | 177 |
Hypersomniab | 46.83 | 2692 | 40.86 | 974 | 100 | 817 |
Psychomotor retardationa | 40.76 | 2343 | 61.37 | 1463 | 30.23 | 247 |
Psychomotor agitationa | 37.50 | 2156 | 60.74 | 1448 | 20.20 | 165 |
Fatigue | 84.71 | 4870 | 84.94 | 2025 | 92.66 | 757 |
Worthlessness | 62.55 | 3596 | 74.20 | 1769 | 59.73 | 488 |
Guilta | 58.13 | 3342 | 81.92 | 1953 | 47.49 | 388 |
Diminished concentration | 84.71 | 4870 | 91.99 | 2193 | 80.78 | 660 |
Indecisiveness | 75.77 | 4356 | 85.19 | 2031 | 71.60 | 585 |
Suicidal ideation/Thoughts of dying | 59.51 | 3421 | 65.18 | 1554 | 56.55 | 462 |
Suicide attempt | 11.05 | 635 | 14.60 | 348 | 8.94 | 73 |