Table 1 Demographic, clinical information, and cognition performance of healthy controls and SCZ patients

Gender

 Male, n (%)

33(57.89)

42(56.76)

0.017

0.896

 Female, n (%)

24(42.11)

32(43.24)

Age, year, M ± SD

27.39 ± 6.06

27.26 ± 7.39

-0.419

0.676

BMI, kg/m², M ± SD

21.60 ± 2.60

20.76 ± 2.67

1.791

0.076

Smoking

 Yes, n (%)

12(21.05)

16(21.62)

0.006

0.937

 No, n (%)

45(78.95)

58(78.38)

Marriage

 Yes, n (%)

45(78.95)

53(71.62)

0.917

0.338

 No, n (%)

12(21.05)

21(28.38)

Education, year, M ± SD

15.72 ± 1.57

12.26 ± 3.35

7.851

< 0.001

Primary or recurrent

 Primary episode, n (%)

-

58(78.38)

-

-

 Recurrent episode, n (%)

-

16(21.62)

Illness duration, month, M ± SD

-

14.51 ± 19.44

-

-

Equivalent drug dose, mg/d, M ± SD

-

6.36 ± 4.62

-

-

Total PANSS

-

90.59 ± 14.19

-

-

 Positive symptom

-

12.51 ± 3.63

-

-

 Negative symptom

-

19.55 ± 5.65

-

-

 Cognitive defect

-

10.36 ± 3.22

-

-

 Excited symptom

-

10.36 ± 3.35

-

-

 Depressive symptom

-

8.61 ± 3.28

-

-

Total MCCB

257.00 ± 54.46

174.57 ± 69.51

54.400

< 0.001

 SCT

49.46 ± 16.00

37.65 ± 13.44

21.038

< 0.001

 HVLT

41.39 ± 11.34

30.43 ± 14.35

22.402

< 0.001

 SST

33.93 ± 14.59

21.93 ± 12.39

25.854

< 0.001

 NAB

43.72 ± 17.18

25.35 ± 18.76

33.183

< 0.001

 BVMT

44.47 ± 15.34

30.82 ± 16.50

23.411

< 0.001

 SF

44.04 ± 15.66

28.38 ± 16.22

30.907

< 0.001