Table 3 Opiate use characteristics by presence and severity of opioid use disorder
Opiate use characteristics | Opiate users w/o Disorder (N = 190) | Opioid use disorder | P for trend by severity†| ||||
|---|---|---|---|---|---|---|---|
All (N = 261) | Mild (N = 144) | Moderate (N = 71) | Severe (N = 46) | ||||
Age of start opiate use (Mean ± SD) | 38.8 ± 12.6 | 35.1 ± 12.4** | 37.9 ± 13.0 | 32.7 ± 11.0 | 30.1 ± 9.9 | < 0.001 | |
Current opiate dose, n (%) (gram per week) a | Q1 (< 1.4) | 92 (49.4) | 63 (24.7)** | 38 (26.7) | 12 (17.1) | 13 (30.2) | 0.049 |
Q2 (1.4–2.8) | 34 (18.2) | 52 (20.3) | 33 (23.2) | 16 (22.8) | 3 (6.9) | ||
Q3 (2.8-7.0) | 39 (20.9) | 71 (27.8) | 40 (28.1) | 23 (32.8) | 8 (18.6) | ||
Q4 (> 7.0) | 21 (11.2) | 69 (27.0) | 31 (21.8) | 19 (27.1) | 19 (44.1) | ||
Prior opiate dose, n (%) (gram per week) b | Q1 (< 0.6) | 6 (35.5) | 55 (21.4)** | 37 (26.2) | 12 (17.1) | 6 (13.3) | < 0.001 |
|  | Q2 (0.6–2.8) | 56 (30.6) | 85 (33.2) | 54 (38.3) | 21 (30.0) | 10 (22.2) | |
|  | Q3 (2.8–10.5) | 32 (17.4) | 46 (17.9) | 22 (15.6) | 13 (18.5) | 11 (24.4) | |
|  | Q4 (> 10.5) | 30 (16.3) | 70 (27.3) | 28 (19.8) | 24 (34.2) | 18 (40.0) | |
Change in dose (gram/week), mean (SD) c | Â | 0.13 (4.6) | 1.7 (4.9)** | 2.1 (4.9) | 1.2 (4.7) | 1.5 (5.2) | 0.15 |
Current pattern of opiate use, n (%) | Non- daily | 38 (20.0) | 26 (10.0)** | 14 (9.8) | 3 (4.3) | 9 (19.5) | 0.334 |
Daily | 152 (80.0) | 235 (90.0) | 130 (90.2) | 68 (95.7) | 37 (80.5) | ||
Prior pattern of opiate use, n (%) b | Non daily | 74 (40.4) | 80 (31.2)* | 49 (34.7) | 21 (30.0) | 10 (22.2) | 0.128 |
| Â | Daily | 109 (59.5) | 176 (68.7) | 92 (65.2) | 49 (70.0) | 35 (77.7) | |
Current type of the opiate, n (%) d | Opium only | 88 (50.2) | 109 (46.1) | 67 (50.3) | 31 (46.2) | 11 (30.5) | 0.070 |
Shire ± opium | 87 (49.7) | 127 (53.1) | 66 (49.6) | 36 (53.7) | 25 (69.4) | ||
Prior type of the opiate, n (%) b | Opium only | 162 (88.5) | 219 (85.5) | 124 (87.9) | 59 (84.2) | 36 (80.0) | 0.180 |
|  | Shire ± opium | 21 (11.4) | 37 (14.4) | 17 (12.0) | 11 (15.7) | 9 (20.0) | |
Current route of opiate use, n (%) e | Smoke only | 99 (55.3) | 82 (33.8)** | 51 (37.7) | 24 (35.2) | 7 (17.9) | < 0.01 |
Oral only | 74 (41.3) | 132 (54.5) | 73 (54.0) | 37 (54.4) | 22 (56.4) | ||
Dual | 6 (3.3) | 28 (11.5) | 11 (8.1) | 7 (10.2) | 10 (25.6) | ||
Prior route of opiate use, n (%) b | Smoke only | 146 (79.7) | 174 (67.9)* | 100 (70.9) | 47 (67.1) | 27 (60.0) | 0.165 |
| Â | Oral only | 34 (18.5) | 74 (28.9) | 37 (26.2) | 22 (31.4) | 15 (33.3) | |
| Â | Dual | 3 (1.6) | 8 (3.1) | 4 (2.8) | 1 (1.4) | 3 (6.6) | |
Change in route, n (%) d | Still smoke | 87 (50.2) | 79 (33.1)** | 49 (36.8) | 24 (35.8) | 6 (15.7) | 0.075 |
Still oral | 30 (17.3) | 72 (30.2) | 37 (27.8) | 22 (32.8) | 13 (34.2) | ||
Change from smoke | 50 (28.9) | 78 (32.7) | 43 (32.3) | 20 (29.8) | 15 (39.4) | ||
Change from oral | 6 (3.4) | 9 (3.7) | 4 (3.0) | 1 (1.4) | 4 (10.5) | ||