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Table 2 Characteristics of the included studies

From: Efficacy of psychosocial interventions to reduce affective symptoms in sexual and gender minorities: a systematic review and meta-analysis of randomized controlled trials

Study (year)

Study setting

Measure

Primary health outcome

Participant mean age (SD/range)

Description of sample (e.g., LGBTIQ status/identification)

Sample size (Experimental group/control group)

Intervention name

Control group

Intervention type

Craig, S. L. (2021) [22]

Canada

BDI-II, PCI-A, RCS, SAMA, HS

Depression, hope, coping, and stress assessment

22.44 (14–29)

Sexual Minority Adolescents

138,97/41

AFFIRM

Waiting

Group intervention, LGB-affirming cognitive behavioral therapy eight times a week for two hours with no follow-up

Pachankis, J.E. (2015) [32]

America

AUDIT, CESD, ODSIS, OASIS, SCS, SSSE, TLFB, MOGS, GRS, IHP, SOCS, DERS, MSPSS, RAS

Depression, anxiety, distress, and co-occurring health risks (i.e., alcohol use, compulsive sexual behavior, condomless sex)

26 (18–35)

Gay, Bisexual Cisgender Male

63,32/31

ESTEEM

Waiting

Individual intervention, LGB-affirming cognitive behavioral therapy, ten sessions, 3-month follow-up

Pachankis, J. E. (2020) [33]

America

CES-D, BSI, ODSIS, OASIS…

Depression, anxiety, distress, minority stress, alcohol use

25.58 (18–35) (3.26)

Sexual Minority Women

60,30/30

EQuIP

Waiting

Individuals, LGB-Affirming Cognitive Behavioral Therapy, 10 weeks

Pachankis, J. E. (2020) [23]

America

CESD, BSI, BAI, SIDAS…

Depression, anxiety, painful alcohol use, suicidal ideation, LGBTQ victimization…

23.68 (18–29) (3.11)

Sexual Minority Adolescents

72,36/36

Expressive writing

Conventional treatment

Online, write once a day for 20 min for three consecutive days, in three stages, with a 3-month follow-up

Antoni, M. H. (2000) [34]

America

HARS, HRSD, DSM-III-R, POMS

Depression, anxiety, and 24-h urinary-free cortisol levels

36.43 (18—55)

gay or bisexual men living with HIV

59,40/19

CBSM

Waiting

Group intervention, 10 weeks

Antoni, M. H. (2000) [35]

America

HARS, HRSD, DSM-III-R, SCID-NP-HIV, POMS, PSS…

Anxiety, perceived stress, 24-h urinary catecholamine levels, and t-lymphocyte subsets

35.97 (18–55)

gay or bisexual men living with HIV

73,47/26

CBSM

Waiting

Group intervention, 10 weeks

Blashill, A. J. (2017) [36]

America

BABS, BIDQ, MADRS, GAF, DSM-IV…

body image disturbance, ART compliance, depression (MADRS), and global functioning (GAF)

46.68 (18–65) (10.51)

gay or bisexual men living with HIV

44,22/22

CBT-BISC

Conventional treatment

Individual intervention with weekly meetings over 3 months (12 phases in total). Each duration lasted approximately 50 min with 6-month follow-up

Carrico, A. W. (2006) [37]

America

POMS, COPE…

Depression, coping strategies, medication adherence…

18–65

gay or bisexual men living with HIV

130,76/54

CBSM

Conventional treatment

CBSM group intervention. Attendance at 135-min sessions per week for ten weeks, with follow-up from June to December

Carrico, A. W. (2005) [24]

America

POM, SPS

Depression, perceived social support, and herpesvirus immunoglobulin G (IgG) antibody titers

34.9 (6.6)

gay or bisexual men living with HIV and on HAART

49,31/18

CBSM

Waiting

CBSM group intervention. Attendance at 135-min sessions per week for ten weeks, with follow-up during 6–12 months

Carrico, A. W. (2005) [38]

America

LES, BDI, SPS, COPE

Depression, perceived social support

35.6(7.2)

gay or bisexual men living with HIV

129,83/46

CBSM

Conventional treatment

CBSM group intervention. Attended weekly 135-min sessions for ten weeks, with a 6-month follow-up

Gayner, B. (2012) [39]

Canada

IES, HADS, PANAS, TMS

Depression, anxiety positive emotions, positive thinking

43.77 (18–70)

gay living with HIV

117,78/39

MBSR

Conventional treatment

Eight 3-h group sessions and one day retreat per week, six days per week for eight weeks. six-month follow-up

Lutgendorf, S. K. (1997) [40]

America

BDI, POMS

Depression, anxiety, physiological indicators

36.75 (20–49)

gay living with HIV

40,22/18

CBSM

Waiting

CBSM group intervention. Attended 135 min of sessions per week for 10 weeks

Millard, T. (2016) [41, 42]

Australia

PROQOL-HIV, heiQ, SF-12, DASS, DSSI, MAH

Pain, quality of life

42.3 (10.4)

gay or MSM living with HIV

132,68/64

Positive Outlook Program

Conventional treatment

online self-management group intervention, participants were encouraged to log into the program for approximately 90 min per week for more than 7 weeks. 12-week follow-up

Williams, J. K. (2013) [43]

America

CSA, PDS, BDI-II

Depression, PTSD, sexual risk behavior…stress biomarkers

46.6(8.3)

African American bisexual men or MSMW living with HIV

88,44/44

ES-HIM

Conventional treatment

6 group sessions lasting 2 h each over 3 weeks with 6-month follow-up

  1. BDI-II Beck depression inventory-II. BCI Brief COPE Inventory. PCI-A Proactive coping inventory for adolescents-A. RCS Reflective coping subscale. SAMA Stress appraisal measure for adolescents. HS Hope scale. AUDIT Alcohol Use Disorders Identification. CESD Center for Epidemiological Studies Depression Scale. ODSIS Overall Depression Severity & Impairment Scale. OASIS Overall Anxiety Severity & Impairment Scale. SCS Sexual Compulsivity Scale. SSSE Safer Sex Self-Efficacy Questionnaire. TLFB 90-day Time Line Follow Back. HRSD Hamilton Rating Scale for Depression. POMS The Profile of Mood States. TMD Total Mood Disturbance. PSS Perceived Stress Scale. PROQOL-HIV HIV-related quality of life. MADRS Montgomery-Asberg Depression Rating Scale. LES Life Experiences Survey. PANAS Positive and Negative Affect Schedule. IES The Impact of Event Scale. DASS Depression Anxiety and Stress Scale. DSSI Duke Social Support Index. HeiQ Health Education Impact Questionnaire. CSA Childhood sexual abuse. PDS Posttraumatic Diagnostic Scale