Investigation of carotid intima-media thickness in patients with schizophrenia

BMC Psychiatry

Table 1 Comparison of Sociodemographic Features and Electrocardiographic Parameters of Patients Diagnosed with Schizophrenia and Healthy Controls

	SCZ (n = 51) M ± SD or n (%) or Med. (Min:Max)	HCs (n = 55) M ± SD or n (%) or Med. (Min:Max)	Statistic	p	OR	%95 CI Lower/Upper
Age	37.24 ± 7.22	38.26 ± 7.46		0.685¹		0.30 / 2.9
Gender				0.478²	1.224	0.23 / 2.71
Female	20 (39.2)	25 (45.6)
Male	31 (60.8)	30 (54.4)
Smoking	38 (74.5)	28 (50.9)		*0.035*²	*6.302*	*5.306 / 9.2*
BMI	26.9 ± 4.9	26.2 ± 4.4		0.684¹		0.023 / 19.4
Systolic blood pressure, mmHg	123.4 ± 7.26	117.6 ± 6.46		0.522¹		0.135 / 46.8
Diastolic blood pressure, mmHg	73.4 ± 5.18	69.6 ± 4.64		0.604²		0.261 / 8.1
LVEF, %	62.5 ± 4.6	64.6 ± 3.8		0.816³		0.024 / 4.6
Heart rate, bpm	82.4 ± 10.36	79.6 ± 11.86		0.206¹		0.015 / 9.7
QRS, msec	91.27 ± 9.61	92.91 ± 9.63	0.564	0.576¹		0.109 / 4.1
QT, msec	367.82 ± 34.40	346.64 ± 29.91	-2.179	0.035¹		0.001 / 4.9
QTc, msec	407 (377–472)	410 (376–444)	0.096	0.925³		0.406 / 3.7
CIMT-left	0.86 ± 0.15	0.76 ± 0.06	-2.873	*0.006*¹		*7.190 / 11.181*
CIMT-right	0.87 ± 0.15	0.75 ± 0.06	-3.325	*0.002*¹		*12.760 / 31.318*

SCZ, schizophrenia; HCs, healthy controls; LVEF, left ventricular ejection fraction; QTc, corrected QT interval; CIMT, carotid intima media thickness
¹Independent t test was used. ²Chi-square test was used. ³Mann-Whitney U test was used. p < 0.05 was accepted as statistically significant. Multivariable logistic regression model was created (Cox & Snell R²: 0.46; Nagelkerke R²: 0.62)

ISSN: 1471-244X