Table 1 Demographic and clinical data at inclusion and during the study period
Demographic and clinical data for participants during the study | MDD | nonMDD | MDD vs. nonMDD | ||||||
|---|---|---|---|---|---|---|---|---|---|
Baseline | 4 weeks | 12 weeks | p-value | Baseline | 4 weeks | 12 weeks | p-value | p-value | |
Age (years) | 20.9 ± 4.2 |  |  |  | 23.7 ± 10.7 |  |  |  | 0,001 |
Gender (% female) | 76% (16/21) | Â | Â | Â | 83% (25/30) | Â | Â | Â | 0,66 |
BMI (kg/m2) | 24.4 ± 5.1 |  |  |  | 23.0 ± 2.8 |  |  |  | 0,168 |
Smoking (yes) | 20% (4/21) | Â | Â | Â | 20% (6/30) | Â | Â | Â | 0,914 |
MDI | 40.3 ± 6.9 | 35.5 ± 8.2 | 29.4 ± 12.1 | *0.13 / § 0.02 | 4.9 ± 4.2 | 3.7 ± 2.7 | 5.0 ± 4.4 | *0.03 / § 0.45 | < 0.0001 |
Active antidepressant medical treatment (yes) | 0% (0/21) | 85.7% (12/14) | 83.3% (10/12) | Â | 0% (0/30) | 0% (0/30) | 0% (0/30) | Â | Â |
Gastrointestinal symptoms (yes) | 50% (10/21) | 64. % (9/14) | 58.3% (7/12) | Â | 10% (3/30) | 6.7% (2/30) | 10% (3/30) | Â | Â |
Bristol Stool Scale Score | 3.5 ± 0.6 | 3,3 ± 1,0 | 3.4 ± 1.2 | *0.18 / § 0.53 | 3.5 ± 0.6 | 3.7 ± 0.6 | 3.7 ± 0.8 | *0.33 / § 0.41 | 0,85 |