Table 4 Characteristic of patients with lithium-induced chronic kidney disease (N = 6)
Case | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
Gender | Female | Female | Male | Male | Female | Male |
Psychiatric diagnosis | Schizoaffective | Bipolar | Cyclothymia | Bipolar | Bipolar | Bipolar |
Age when starting lithium (years) | 44 | 44 | 60 | 27 | 47 | 53 |
Age at the end of the study (years) | 61 | 65 | 64 | 48 | 67 | 65 |
Body weight (kg) | 54.1 | 62 | 81 | 86.9 | 67.2 | 79.7 |
Physical illness | No | DM, HT | HT | DLP, DM, HT | DLP | HT |
Receiving Nephrotoxic medication | No | No | No | No | No | No |
Presence of acute kidney injury | No | No | No | No | No | No |
Lithium dosage at the diagnosis of CKD (mg/d) | 900 | 300 | 900 | 600 | 600 | 900 |
Lithium compliance | Poor | Poor | Good | Poor | Good | Good |
Duration using lithium (years) | 12 | 15 | 3 | 18 | 15 | 5 |
Presence of lithium intoxication | Yes | No | No | No | No | Yes |
Presence of lithium side effect | Tremor Dysarthria | Tremor | No | Tremor | No | No |
Serum lithium level (mEq/L) | 1.54 | 0.81 | No data | 1.23 | 0.6 | 1.59 |
CKD stage | 3a | 3a | 5 | 3a | 3a | 3a |