Patients with first-episode psychosis in northern Taiwan: neurocognitive performance and niacin response profile in comparison with schizophrenia patients of different familial loadings and relationship with clinical features

Table 5 Spearman’s correlation of baseline measures with clinical features at baseline among patients with first-episode psychosis (N = 80)

Z-scores	PANSS positive r (P value)	PANSS negative r (P value)	PSP r (P value)
Continuous Performance Test
Undegraded d’	−0.35 (0.004)^*	−0.50 (< 0.001)^*	0.35 (0.005)^*
Degraded d’	−0.13 (0.30)	−0.29 (0.02)	0.29 (0.02)
Wisconsin Card Sorting Test
−Perseverative errors^a	−0.33 (0.006)^*	−0.45 (< 0.001)^*	0.23 (0.06)
Categories achieved	−0.38 (0.002)^*	−0.43 (< 0.001)^*	0.27 (0.03)
Niacin response (NR) abnormality
Volumetric NR for 0.1 M and 0.01 M	−0.26 (0.04)	−0.07 (0.60)	0.05 (0.69)
Minor physical anomalies and craniofacial features
Facial width	0.02 (0.87)	0.12 (0.32)	0.00 (0.98)
Lower facial height	−0.01 (0.96)	0.07 (0.60)	0.08 (0.55)
Mouth score	0.03 (0.81)	0.00 (0.99)	−0.01 (0.92)

^aTransformed to a negative value to let a more negative Z-score represent a greater impairment compared to the comparison group and hence denoted as − perseverative errors
^*P < (0.05/3
0.016), with correction for multiple testing for variables of clinical features
Abbreviations: PANSS = Positive and Negative Syndrome Scale; PSP = Personal and Social Performance; NR = niacin response

ISSN: 1471-244X