BMC Psychiatry

Table 1 Impact of cytokines on depression within 3 months

From: Impacts of inflammatory cytokines on depression: a cohort study

	PHQ-9
	Month 1				Month 2				Month 3
	Model 1		Model 2		Model 1		Model 2		Model 1		Model 2
	B	P	B	P	B	P	B	P	B	P	B	P
IL-1β	0.75	0.04*	0.43	0.14	1.07	< 0.01*	0.92	< 0.01*	1.05	< 0.01*	0.86	0.02*
IL-2	1.41	0.01*	0.76	0.11	0.28	0.63	-0.22	0.70	0.11	0.86	-0.56	0.37
IL-4	0.91	0.01*	0.43	0.15	0.47	0.22	0.12	0.74	0.45	0.26	0.04	0.91
IL-5	0.94	0.17	0.52	0.31	-0.23	0.73	-0.60	0.33	-0.40	0.58	-0.64	0.34
IL-6	0.02	0.82	0.05	0.52	0.01	0.87	0.06	0.54	-0.02	0.81	-0.01	0.92
IL-8	-0.01	0.50	0.00	0.93	0.00	0.76	0.00	0.78	0.00	0.70	0.00	0.92
IL-10	0.41	0.16	0.31	0.16	-0.04	0.89	-0.12	0.64	-0.12	0.69	-0.17	0.56
IL-12P70	1.88	0.21	1.30	0.28	0.02	0.98	-0.55	0.69	-0.11	0.94	-1.04	0.50
IL-17 A	0.53	0.05	0.24	0.25	0.13	0.62	-0.07	0.77	0.11	0.70	-0.13	0.63
IL-17 F	0.16	0.83	0.00	0.99	0.46	0.54	0.38	0.57	-0.12	0.87	-0.27	0.71
IL-22	0.08	0.50	0.06	0.47	0.08	0.48	0.06	0.55	0.02	0.85	-0.01	0.92
TNF-α	0.30	0.39	0.27	0.30	0.43	0.47	0.71	0.22	0.49	0.43	0.45	0.47
TNF-β	0.68	0.26	0.38	0.42	0.32	0.59	0.03	0.94	0.38	0.55	0.15	0.79
IFN-γ	0.98	0.18	0.34	0.54	0.71	0.33	0.27	0.69	0.51	0.50	-0.14	0.84

Model 1: adjust for nothing
Model 2: adjust for age, BMI, education, antidepressant drugs, social support, life stress and PHQ-9 at baseline
PHQ-9, Patient Health Questionnaire-9; BMI, body mass index
*P < 0.05

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