Table 2 Mixed model analysis of the effect of Internet-delivered cognitive behavioural therapy (iCBT) compared to psychoeducation on cardiac anxiety and secondary outcomes, presented in estimated marginal means

CAQ^b

29.4

30.8

.959

0.31

Baseline

36.4

-

36.3

36.4

-

5 weeks

30.3

 < .001

29.8

30.8

.493

3 months

29.0

 < .001

28.1

30.0

.312

6 months

28.1

 < .001

27.1

29.1

.273

12 months

26.8

 < .001

25.8

27.8

.256

BSQ^c

38.2

38.5

.618

0.40

Baseline

42.7

-

43.3

42.1

-

5 weeks

38.0

 < .001

37.0

39.1

.092

3 months

37.5

 < .001

35.7

37.3

.664

6 months

36.8

 < .001

37.6

35.9

.872

12 months

36.8

 < .001

35.3

38.3

.086

PHQ-9^d

6.6

6.3

.752

0.07

Baseline

7.8

-

8.0

7.6

-

5 weeks

7.0

.515

7.6

6.4

.324

3 months

5.9

.005

6.0

5.8

.901

6 months

6.2

.003

6.1

6.3

.476

12 months

5.4

< .001

5.3

5.5

.546

EQ-VAS^e

61.1

65.7

.030

0.27

Baseline

62.5

-

58.5

66.4

-

5 weeks

61.2

.579

60.0

62.3

.139

3 months

61.9

.304

62.2

61.6

.094

6 months

64.9

.629

60.0

69.9

.642

12 months

66.5

.027

64.9

68.2

.258

Chest pain frequency

10.6

6.7

.005

0.48

Baseline

12.0

-

15.1

8.8

-

5 weeks

11.1

.613

14.2

8.1

.923

3 months

8.1

.003

9.4

6.7

.164

6 months

6.8

< .001

8.7

4.9

.247

12 months

5.2

< .001

5.6

4.8

.009