Table 3 Within group changes (Estimates of Fixed Effects from Linear Mixed Model Analysis) over the 12-month follow-up in the iCBT and psychoeducation groups

Cardiac anxiety

(CAQ)

0 Weeks

36.32

1.109

.00^a

54

36.40

1.214

.00^a

55

5 Weeks

29.81

1.229

-6.504

 < .001

-8.641

-4.367

48

30.83

1.387

-5.569

 < .001

-7.377

-3.762

52

3 Months

27.98

1.467

-8.339

 < .001

-11.043

-5.634

44

30.03

1.644

-6.373

 < .001

-8.602

-4.145

48

6 Months

26.82

1.400

-9.472

 < .001

-12.133

-6.811

45

29.14

1.637

-7.260

 < .001

-9.444

-5.076

48

12 Months

25.58

1.322

-10.736

 < .001

-13.383

-8.089

46

27.84

1.553

-8.556

 < .001

-10.883

-6.230

47

Fear of bodily sensations

(BSQ)

0 Weeks

43.33

1.943

.00^a

54

42.07

1.607

.00^a

55

5 Weeks

36.86

1.509

-6.474

 < .001

-9.427

-3.521

48

39.10

1.703

-2.975

.023

-5.528

-.423

52

3 Months

37.76

1.756

-5.577

 < .001

-8.078

-3.075

44

37.30

1.750

-4.777

.003

-7.907

-1.648

48

6 Months

37.72

1.944

-5.610

 < .001

-8.829

-2.391

45

35.89

1.606

-6.181

 < .001

-9.323

-3.040

48

12 Months

35.43

1.665

-7.908

 < .001

-10.907

-4.909

46

38.27

1.870

-3.803

.061

-7.785

.180

47

Depressive symptoms

(PHQ-9)

0 Weeks

8.00

.768

.00^a

54

7.64

.853

.00^a

55

5 Weeks

7.63

.739

-.374

.485

-1.444

.695

48

6.42

.834

-1.219

.060

-2.491

.053

52

3 Months

6.29

.746

-1.711

 < .001

-2.595

-.827

44

5.77

.784

-1.867

.024

-3.480

-.255

48

6 Months

6.08

.722

-1.925

.002

-3.133

-.717

45

6.31

.722

-1.324

.043

-2.606

-.042

48

12 Months

5.33

.579

-2.667

 < .001

-3.805

-1.529

46

5.53

.779

-2.104

.005

-3.534

-.673

47

Health-related quality of life

(EQ-VAS)

0 Weeks

58.54

2.760

.00^a

54

66.38

2.266

.00^a

55

5 Weeks

60.18

2.863

1.640

.430

-2.498

5.779

48

62.18

2.908

-4.204

.181

-10.419

2.011

52

3 Months

62.70

3.209

4.166

.235

-2.788

11.120

44

61.84

3.500

-4.542

.211

-11.742

2.657

48

6 Months

59.63

3.082

1.088

.684

-4.255

6.432

45

69.48

2.613

3.094

.359

-3.620

9.808

48

12 Months

64.66

2.893

6.121

.012

1.410

10.833

46

67.95

2.754

1.572

.620

-4.749

7.893

47

Chest pain frequency

(Self-developed question)

0 Weeks

15.15

1.704

.00^a

54

8.99

1.414

.00^a

54

5 Weeks

13.81

2.474

-1.335

.597

-6.373

3.704

47

8.15

1.436

-.845

.473

-3.193

1.503

52

3 Months

9.25

2.000

-5.899

.005

-9.980

-1.817

44

6.84

1.602

-2.156

.199

-5.490

1.177

48

6 Months

8.90

1.636

-6.240

 < .001

-9.660

-2.819

45

4.92

.976

-4.085

.004

-6.808

-1.361

48

12 Months

5.82

1.201

-9.329

 < .001

-12.613

-6.045

46

4.79

1.088

-4.207

.002

-6.766

-1.647

47