Table 2 Baseline levels of ACTH, cortisol and HPA axis related-genes expression between PD patients and controls
Variable | PD (n = 77) | Controls(n = 82) | t/Z-value | p-value |
|---|---|---|---|---|
ACTH(pg/mL) | 35.99 ± 13.93 | 20.79 ± 7.88 | -8.399 | 0.000 |
Cortisol(ug/dL) | 12.10 ± 4.33 | 8.63 ± 3.15 | -5.746 | 0.000 |
NR3C1 | 0.025 (0.008–0.038) | 0.028 (0.020–0.040) | -1.020 | 0.308 |
FKBP51 | 0.155 (0.086–0.237) | 0.073 (0.041–0.137) | -4.701 | 0.000 |
HSP90 | 0.013 (0.007–0.023) | 0.014 (0.008–0.016) | -0.458 | 0.647 |
POMC | 0.004 (0.002–0.008) | 0.003 (0.002–0.006) | -1.627 | 0.104 |