Table 2 Separate models for multivariable analysis of brain volumes (z-scores) and behavioral inhibition scores, adjusting for sociodemographic indicators and child’s anxiety disorder
Candidate brain structure | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
β | 95% CI | β | 95% CI | β | 95% CI | |
Whole brain | 0.042 | -0.051 0.135 | 0.048 | -0.044 0.141 | 0.049 | -0.044 0.142 |
Total cortical | 0.003 | -0.141 0.146 | 0.012 | -0.131 0.156 | 0.009 | -0.135 0.152 |
Total cerebral WM | -0.152 | -0.281 -0.023 | -0.148 | -0.277 -0.019 | -0.142 | -0.270 -0.013 |
Total amygdala | 0.038 | -0.061 0.138 | 0.045 | -0.054 0.144 | 0.046 | -0.052 0.145 |
Total hippocampus | 0.094 | -0.008 0.196 | 0.095 | -0.007 0.197 | 0.099 | -0.002 0.202 |
Total accumbens | -0.005 | -0.089 0.079 | -0.0005 | -0.084 0.083 | 0.001 | -0.083 0.085 |
Total insula | -0.071 | -0.176 0.035 | -0.065 | -0.171 0.039 | -0.066 | -0.171 0.039 |
Total anterior cingulate | -0.039 | -0.123 0.044 | -0.037 | -0.120 0.046 | -0.038 | -0.121 0.045 |
Total posterior cingulate | -0.040 | -0.136 0.056 | -0.036 | -0.132 0.060 | -0.033 | -0.129 0.063 |
Total orbitofrontal | -0.012 | -0.111 0.087 | -0.009 | -0.108 0.090 | -0.011 | -0.110 0.088 |
Total prefrontal cortex | -0.001 | -0.121 0.119 | 0.004 | -0.116 0.125 | 0.004 | -0.116 0.124 |
Total caudate | -0.056 | -0.146 0.035 | -0.052 | -0.143 0.038 | -0.055 | -0.146 0.035 |
Total putamen | -0.089 | -0.183 0.005 | -0.091 | -0.185 0.003 | -0.087 | -0.181 0.007 |
Total thalamus | -0.168 | -0.291 -0.044 | -0.172 | -0.295 -0.049 | -0.163 | -0.286 -0.039 |
Total precuneus | 0.076 | -0.030 0.182 | 0.080 | -0.026 0.186 | 0.079 | -0.027 0.185 |
Total cuneus | -0.045 | -0.136 0.046 | -0.042 | -0.133 0.049 | -0.045 | -0.136 0.046 |
Total entorhinal | 0.011 | -0.072 0.095 | 0.013 | -0.071 0.096 | 0.011 | -0.073 0.094 |
Total Parahippocampal | 0.044 | -0.044 0.131 | 0.047 | -0.041 0.134 | 0.043 | -0.044 0.131 |
Total precentral | -0.068 | -0.175 0.038 | -0.061 | -0.168 0.045 | -0.066 | -0.172 0.041 |
Total pallidum | -0.019 | -0.111 0.072 | -0.017 | -0.108 0.075 | -0.020 | -0.111 0.071 |