Asparagine reduces the risk of schizophrenia: a bidirectional two-sample mendelian randomization study of aspartate, asparagine and schizophrenia

Table 1 Results of various analytical methods

Exposure	Outcome	Method	Nsnp	OR		P
Aspartate	Schizophrenia	MR Egger	3	0.477	1.320	0.674
		Weighted median	3	1.089	0.338	0.802
		IVW	3	1.221	0.474	0.674
		Weighted mode Egger intercept	3	1.050	0.376 0.04	0.907 0.579
Schizophrenia	Aspartate	MR Egger	90	0.997	0.021	0.221
		Weighted median	90	1.002	0.007	0.785
		IVW	90	0.999	0.005	0.841
		Weighted mode Egger intercept	90	0.993	0.008 0.002	0.672 0.226
Asparagine	Schizophrenia	MR Egger	24	0.408	0.664	0.191
		Weighted median	24	0.478	0.334	0.027
		IVW	24	0.485	0.315	0.022
		Weighted mode Egger intercept	24	0.522	0.428 0.007	0.142 0.768
Schizophrenia	Asparagine	MR Egger	90	0.995	0.015	0.714
		Weighted median	90	1.003	0.004	0.491
		IVW	90	1.005	0.003	0.132
		Weighted mode Egger intercept	90	1.001	0.009 0.001	0.941 0.474

ISSN: 1471-244X