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  1. Polypharmacy increases the risk of pharmacological interactions, prevalence of secondary effects and with this the lack of adherence to treatment. It is estimated that between 10 and 40% of patients hospitaliz...

    Authors: J. Carmona-Huerta, S. Castiello-de Obeso, J. Ramírez-Palomino, R. Duran-Gutiérrez, D. Cardona-Muller, F. Grover-Paez, P. Fernández-Dorantes and R. Medina-Dávalos
    Citation: BMC Psychiatry 2019 19:78
  2. This study determined the effects of a novel combination of vitamin D and probiotic on metabolic and clinical symptoms in chronic schizophrenia.

    Authors: Amir Ghaderi, Hamid Reza Banafshe, Naghmeh Mirhosseini, Mohamad Moradi, Mohammad-Amin Karimi, Fateme Mehrzad, Fereshteh Bahmani and Zatollah Asemi
    Citation: BMC Psychiatry 2019 19:77
  3. Clinical Practice Guidelines (CPGs) should follow an adequate methodology using an evidence-based approach in order to provide reliable recommendations. However, little is known regarding the quality of CPGs f...

    Authors: Jessica Hanae Zafra-Tanaka, Sergio Goicochea-Lugo, David Villarreal-Zegarra and Alvaro Taype-Rondan
    Citation: BMC Psychiatry 2019 19:76
  4. Family caregivers play crucial roles in taking care of people experiencing schizophrenia in the community. The burdens on and needs of caregivers of these patients should be emphasized. This study aimed to exp...

    Authors: Lifen Chen, Yali Zhao, Juan Tang, Guanghui Jin, Yanli Liu, Xuexue Zhao, Chao Chen and Xiaoqin Lu
    Citation: BMC Psychiatry 2019 19:75
  5. The medical-ethical dilemmas related to euthanasia and physician-assisted suicide (EAS) in psychiatric patients are highly relevant in an international context. EAS in psychiatric patients appears to become mo...

    Authors: Kirsten Evenblij, H. Roeline W. Pasman, Rosalie Pronk and Bregje D. Onwuteaka-Philipsen
    Citation: BMC Psychiatry 2019 19:74
  6. Rebound cholinergic syndrome is a rare, but well known unwanted phenomenon occurring after abrupt clozapine discontinuation. There have been previous reported cases of cholinergic rebound in the literature; ho...

    Authors: Andrea Galova, Patricia Berney, Jules Desmeules, Ioannis Sergentanis and Marie Besson
    Citation: BMC Psychiatry 2019 19:73
  7. There is a growing body of literature highlighting the role that wearable and mobile remote measurement technology (RMT) can play in measuring symptoms of major depressive disorder (MDD). Outcomes assessment t...

    Authors: F. Matcham, C. Barattieri di San Pietro, V. Bulgari, G. de Girolamo, R. Dobson, H. Eriksson, A. A. Folarin, J. M. Haro, M. Kerz, F. Lamers, Q. Li, N. V. Manyakov, D. C. Mohr, I. Myin-Germeys, V. Narayan, Penninx BWJH…
    Citation: BMC Psychiatry 2019 19:72
  8. Mental distress is becoming a common health problem in Ethiopia. The prevalence of mental distress is higher among university students than the general population. However, there is inadequate information in t...

    Authors: Tadis Brhane Tesfahunegn and Etsay Hailu Gebremariam
    Citation: BMC Psychiatry 2019 19:71
  9. Executive functioning impairment is common in substance use disorder and is a major risk factor for poor treatment outcomes, including treatment drop-out and relapse. Cognitive remediation interventions seek t...

    Authors: Jamie Berry, Isabella Jacomb, Jo Lunn, Antoinette Sedwell, Anthony Shakeshaft, Peter J Kelly, Pooria Sarrami, Megan James, Skye Russell, Talia Nardo, Daniel Barker and Jennifer Holmes
    Citation: BMC Psychiatry 2019 19:70
  10. Phobic anxiety disorders are among the most prevalent psychiatric disorders and are burdensome in terms of loss of quality of life and work productivity. Evidence-based treatments are relatively successful in ...

    Authors: Febe E. van der Flier, Caroline M. B. Kwee, Danielle C. Cath, Neeltje M. Batelaan, Lucianne Groenink, Puck Duits, Date C. van der Veen, Anton J. L. M. van Balkom and Johanna M. P. Baas
    Citation: BMC Psychiatry 2019 19:69
  11. Members of the public can potentially take action to assist someone in their social network who is distressed and at risk of suicide. The present study used data from a community survey to examine training exp...

    Authors: Anthony F. Jorm, Angela Nicholas, Jane Pirkis, Alyssia Rossetto, Julie-Anne Fischer and Nicola J. Reavley
    Citation: BMC Psychiatry 2019 19:68
  12. Primary brain calcification (PBC), a neurodegenerative disorder with characteristic calcium deposits in the basal ganglia and other brain areas, typically presents with various neurological and psychiatric sym...

    Authors: Barbara Plemeniti Tololeski, Maruša Debeljak, Mirjana Perkovič Benedik, Tristan Rigler, Marinos Kyriakopoulos, Primož Kotnik, Katarina Šurlan Popovič and Maja Drobnič Radobuljac
    Citation: BMC Psychiatry 2019 19:67
  13. The World Health Organization (WHO) has included comorbidity between depression and a chronic disease among the 10 leading global health priorities. Although there is a high prevalence of multimorbidity, healt...

    Authors: Alicia Monreal-Bartolomé, Alberto Barceló-Soler, Adoración Castro, Mª. Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, Maria Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M. Baños, Yolanda López-Del-Hoyo and Javier García-Campayo
    Citation: BMC Psychiatry 2019 19:66
  14. Background: Illness Management and Recovery (IMR) is a curriculum-based rehabilitation program for people with severe mental illness with the short-term aim of improving illness self-management and the long-te...

    Authors: Sofie Bratberg Jensen, Helle Stentoft Dalum, Lisa Korsbek, Carsten Hjorthøj, John Hagel Mikkelsen, Karin Thomsen, Kristen Kistrup, Mette Olander, Jane Lindschou, Kim T. Mueser, Merete Nordentoft and Lene Falgaard Eplov
    Citation: BMC Psychiatry 2019 19:65
  15. Since anxiety and depressive disorders often recur, self-management competencies are crucial for improving the long-term course of anxiety and depressive disorders. However, few relapse prevention programmes a...

    Authors: Esther Krijnen-de Bruin, Anna D. T. Muntingh, Adriaan W. Hoogendoorn, Annemieke van Straten, Neeltje M. Batelaan, Otto R. Maarsingh, Anton J. L. M. van Balkom and Berno van Meijel
    Citation: BMC Psychiatry 2019 19:64
  16. The role of dietary patterns in the prevention of unipolar depression has been analyzed in several epidemiological studies. The primary aims of this study are to determine the effectiveness of an extra-olive o...

    Authors: A. Sánchez-Villegas, B. Cabrera-Suárez, P. Molero, A. González-Pinto, C. Chiclana-Actis, C. Cabrera, F. Lahortiga-Ramos, M. Florido-Rodríguez, P. Vega-Pérez, R. Vega-Pérez, J. Pla, M. J. Calviño-Cabada, F. Ortuño, S. Navarro, Y. Almeida and J. L. Hernández-Fleta
    Citation: BMC Psychiatry 2019 19:63
  17. Calcium voltage-gated channel auxiliary subunit β2 is a protein that, in humans, is encoded by the CACNB2 gene. The β2 subunit is an auxiliary protein of voltage-gated calcium channels, which is predominantly exp...

    Authors: Fang Liu, Xiaohong Gong, Xudong Yao, Lingling Cui, Zhiyang Yin, Chao Li, Yanqing Tang and Fei Wang
    Citation: BMC Psychiatry 2019 19:62
  18. The number of dementia cases is expected to rise exponentially over the years in many parts of the world. Collaborative healthcare partnerships are envisaged as a solution to this problem. Primary care physici...

    Authors: Shan Hui Lai, Tung Tsoi, Chao Tian Tang, Richard Jor Yeong Hui, Kim Kiat Tan, Yehudi Wee Shung Yeo and Ee Heok Kua
    Citation: BMC Psychiatry 2019 19:61
  19. Approximately 84,000 children under the age of 15 years are living with HIV in Malawi. Although the survival rate of children living with HIV in Malawi has improved due to the increased availability of antiret...

    Authors: Fatch W. Kalembo, Garth E. Kendall, Mohammed Ali and Angela F. Chimwaza
    Citation: BMC Psychiatry 2019 19:60
  20. Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The cardinal features of MDD are depressed mood and anhedonia. Anhedonia is defined as a “markedly diminished interest or pleasure ...

    Authors: Vera E. Heininga, Egon Dejonckheere, Marlies Houben, Jasmien Obbels, Pascal Sienaert, Bart Leroy, Joris van Roy and Peter Kuppens
    Citation: BMC Psychiatry 2019 19:59
  21. Depressive symptoms are common in patients with coronary artery disease (CAD) and are associated with an unfavourable outcome. Establishing prognostic patient profiles prior to the beginning of mental health care...

    Authors: Frank Vitinius, Steffen Escherich, Hans-Christian Deter, Martin Hellmich, Jana Jünger, Katja Petrowski, Karl-Heinz Ladwig, Frank Lambertus, Matthias Michal, Cora Weber, Martina de Zwaan, Christoph Herrmann-Lingen, Joram Ronel and Christian Albus
    Citation: BMC Psychiatry 2019 19:57
  22. Little is known about the extent to which post traumatic stress symptoms (PTSS) vary from day to day in individuals with post traumatic stress disorder (PTSD). This study examined the variation of PTSS by day ...

    Authors: Quinn M. Biggs, Robert J. Ursano, Jing Wang, David S. Krantz, Russell B. Carr, Gary H. Wynn, Deborah Probe Adams, Nicole M. Dacuyan and Carol S. Fullerton
    Citation: BMC Psychiatry 2019 19:56
  23. Clinically operated community-based residential rehabilitation units (Community Rehabilitation Units) are resource intensive services supporting a small proportion of the people with severe and persisting ment...

    Authors: Stephen Parker, Gordon Hopkins, Dan Siskind, Meredith Harris, Gemma McKeon, Frances Dark and Harvey Whiteford
    Citation: BMC Psychiatry 2019 19:55
  24. Smoking has played a significant role in the historical culture of mental healthcare settings. Mental health professionals (MHPs) often hold dismissive attitudes regarding the importance of smoking cessation i...

    Authors: Charlie Albert Smith, Ann McNeill, Loren Kock and Lion Shahab
    Citation: BMC Psychiatry 2019 19:54
  25. Complementary and Alternative Medicine (CAM) is widely used both in the general population and for the treatment of somatic and psychiatric disorders. Studies on CAM use among patients with autism spectrum dis...

    Authors: Juliana Höfer, Falk Hoffmann, Inge Kamp-Becker, Charlotte Küpper, Luise Poustka, Stefan Roepke, Veit Roessner, Sanna Stroth, Nicole Wolff and Christian J. Bachmann
    Citation: BMC Psychiatry 2019 19:53
  26. Inpatients with depression have a poor long term outcome with high rates of suicide, high levels of morbidity and frequent re-admission. Current treatment often relies on pharmacological intervention and focus...

    Authors: Ian R. E. Averill, Ben Beaglehole, Katie M. Douglas, Jennifer Jordan, Marie T. Crowe, Maree Inder, Cameron J. Lacey, Christopher M. Frampton, Christopher R. Bowie and Richard J. Porter
    Citation: BMC Psychiatry 2019 19:52
  27. Depression and anxiety is a major public health problem, in Sweden and internationally. Internet-based interventions are increasingly acknowledged as promising approaches for individuals with varying degrees o...

    Authors: Anders Nilsson, Karolina Sörman, Josefin Klingvall, Emma Ovelius, Jonas Lundberg and Clara Hellner
    Citation: BMC Psychiatry 2019 19:51
  28. Recommendations for pharmacological treatments of major depression with specific comorbid psychiatric conditions are lacking.

    Authors: D. Bennabi, A. Yrondi, T. Charpeaud, J.-B. Genty, S. Destouches, S. Lancrenon, N. Allaili, F. Bellivier, T. Bougerol, V. Camus, O. Doumy, J.-M. Dorey, F. Haesebaert, J. Holtzmann, C. Lançon, M. Lefebvre…
    Citation: BMC Psychiatry 2019 19:50
  29. Suicide bereavement is a risk factor for adverse outcomes related to grief, social functioning, mental health and suicidal behaviour. Consequently, suicide bereavement support (i.e., postvention) has been iden...

    Authors: Karl Andriessen, Karolina Krysinska, Nicole T. M. Hill, Lennart Reifels, Jo Robinson, Nicola Reavley and Jane Pirkis
    Citation: BMC Psychiatry 2019 19:49
  30. Parents are vulnerable to psychological distress symptoms in the postpartum period. It is routine to screen for depressive symptoms, but anxiety, stress, fatigue, irritability and insomnia symptoms are less of...

    Authors: Nathan Wilson, Karen Wynter, Clare Anderson, Shanthakumar M. W. Rajaratnam, Jane Fisher and Bei Bei
    Citation: BMC Psychiatry 2019 19:48
  31. Antenatal common mental disorders (CMDs) including anxiety, depressive, adjustment, and somatoform disorders are prevalent worldwide. There is emerging evidence that experiencing a natural disaster might incre...

    Authors: Goma Kumari Khatri, Thach Duc Tran and Jane Fisher
    Citation: BMC Psychiatry 2019 19:47
  32. Anxiety and depressive disorders are common mental disorders. A substantial part of patients does not achieve symptomatic remission after treatment in specialized services. Current care as usual (CAU) for thes...

    Authors: Maringa H. H. Zoun, Bauke Koekkoek, Henny Sinnema, Christina M. van der Feltz-Cornelis, Anton J. L. M. van Balkom, Aart H. Schene, Filip Smit and Jan Spijker
    Citation: BMC Psychiatry 2019 19:46
  33. There is evidence that several intervention types, including psychotherapy, reduce repeat suicide attempts. However, these interventions are less applicable to the heterogeneous patients admitted to emergency ...

    Authors: Masatoshi Inagaki, Yoshitaka Kawashima, Naohiro Yonemoto and Mitsuhiko Yamada
    Citation: BMC Psychiatry 2019 19:44
  34. Adult attention-deficit/hyperactivity disorder (ADHD) is a serious and frequent psychiatric disorder of multifactorial pathogenesis. Several lines of evidence support the idea that ADHD is, in its core, a diso...

    Authors: Peter Sörös, Eliza Hoxhaj, Patricia Borel, Chiharu Sadohara, Bernd Feige, Swantje Matthies, Helge H. O. Müller, Katharina Bachmann, Marcel Schulze and Alexandra Philipsen
    Citation: BMC Psychiatry 2019 19:43
  35. Self-harm and depression are strong risk factors for repeat self-harm and suicide. We aimed to investigate the feasibility of a randomised controlled trial (RCT) of remotely delivered problem-solving cognitive...

    Authors: Kapil Sayal, James Roe, Harriet Ball, Christopher Atha, Catherine Kaylor-Hughes, Boliang Guo, Ellen Townsend and Richard Morriss
    Citation: BMC Psychiatry 2019 19:42
  36. Dog-assisted therapy (DAT) is a non-pharmacological intervention based on the interaction between patients and dogs, which has been proposed to help adults with dementia. However, evidence to support it is lac...

    Authors: Jessica Hanae Zafra-Tanaka, Kevin Pacheco-Barrios, Walter Andree Tellez and Alvaro Taype-Rondan
    Citation: BMC Psychiatry 2019 19:41
  37. Depression and anxiety are prevalent mental disorders among the working population with potentially high personal and financial cost. The overall aim of this study was to test the applicability of an outreach ...

    Authors: Helle Østermark Sørensen, Jan B. Valentin, Malene Krogsgaard Bording, Jens Ivar Larsen, Anelia Larsen and Øyvind Omland
    Citation: BMC Psychiatry 2019 19:40
  38. Web-based mental health applications may be beneficial, but adoption is often low leaving optimal implementation and payment models unclear. This study examined which users were interested in extended access t...

    Authors: Jennifer M. Hensel, James Shaw, Noah M. Ivers, Laura Desveaux, Simone N. Vigod, Zachary Bouck, Nike Onabajo, Payal Agarwal, Geetha Mukerji, Rebecca Yang, Megan Nguyen, Lianne Jeffs, Trevor Jamieson and R. Sacha Bhatia
    Citation: BMC Psychiatry 2019 19:39
  39. Physical illness and mental disorders play a significant role in fatal and non-fatal suicidal behaviour. However, there is no clear evidence for the effect of physical and mental illness co-occurrence (multimo...

    Authors: Katerina Kavalidouª, Daniel J. Smith, Geoff Der and Rory C. O’Connor
    Citation: BMC Psychiatry 2019 19:38
  40. Cardiometabolic health significantly impacts on the mortality of people with severe mental illness. Clozapine has the greatest efficacy for Treatment Resistant Schizophrenia (TRS) but the greatest negative imp...

    Authors: Alex Till and Ed Silva
    Citation: BMC Psychiatry 2019 19:37
  41. The development of digital health interventions (DHIs) for severe mental health problems is fast-paced. Researchers are beginning to consult service users to inform DHIs; however, much of this involvement has ...

    Authors: Natalie Berry, Fiona Lobban and Sandra Bucci
    Citation: BMC Psychiatry 2019 19:35
  42. The aim of this study was to determine the prevalence of neurological disorders and their associated correlates and relations with clinical and behavioural problems among children and adolescents with HIV/AIDS...

    Authors: Richard Stephen Mpango, Godfrey Zari Rukundo, Sylvia Kiwuwa Muyingo, Kenneth D. Gadow, Vikram Patel and Eugene Kinyanda
    Citation: BMC Psychiatry 2019 19:34
  43. The extent of post-mortem detection of specific psychoactive drugs may differ between countries, and may greatly influence the national death register’s classification of manner and cause of death. The main ob...

    Authors: Ida Kathrine Gravensteen, Øivind Ekeberg, Ingemar Thiblin, Karin Helweg-Larsen, Erlend Hem, Sidsel Rogde and Ingvild Maria Tøllefsen
    Citation: BMC Psychiatry 2019 19:33
  44. First-generation antipsychotics (FGAs) are associated with a range of adverse events which can significantly reduce patients’ quality of life and contribute to non-adherence. The aim of this study was to asses...

    Authors: Yirgalem Shewakena Wubeshet, Oumer Sada Mohammed and Tigestu Alemu Desse
    Citation: BMC Psychiatry 2019 19:32
  45. Although the majority of active duty U.S. Army soldiers are full-time personnel in the Active Component (AC), a substantial minority of soldiers on active duty are in the Reserve Components (RCs). These “citiz...

    Authors: James A. Naifeh, Robert J. Ursano, Ronald C. Kessler, Oscar I. Gonzalez, Carol S. Fullerton, Holly B. Herberman Mash, Charlotte A. Riggs-Donovan, Tsz Hin Hinz Ng, Gary H. Wynn, Hieu M. Dinh, Tzu-Cheg Kao, Nancy A. Sampson and Murray B. Stein
    Citation: BMC Psychiatry 2019 19:31
  46. People with a family history of major depressive disorder (MDD) or bipolar disorder (BD) report specific psychoeducational needs that are unmet by existing online interventions. This trial aimed to test whethe...

    Authors: Llewellyn Mills, Bettina Meiser, Raghib Ahmad, Peter R. Schofield, Michelle Peate, Charlene Levitan, Lyndal Trevena, Kristine Barlow-Stewart, Timothy Dobbins, Helen Christensen, Kerry A. Sherman, Kate Dunlop and Philip B. Mitchell
    Citation: BMC Psychiatry 2019 19:29
  47. No study has examined the prevalence of tobacco, other substance use, and symptoms of anxiety and depression, and rates of comorbidities among the orthopaedic trauma population, despite the impact they have on...

    Authors: Sam McCrabb, Amanda L. Baker, John Attia, Zsolt J. Balogh, Natalie Lott, Kerrin Palazzi, Justine Naylor, Ian A. Harris, Christopher M. Doran, Johnson George, Luke Wolfenden, Eliza Skelton and Billie Bonevski
    Citation: BMC Psychiatry 2019 19:28

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