Table 1 Striatal D2 receptor occupancies by DA estimated from receptor imaging studies.
From: Erratum to: Model-based parametric study of frontostriatal abnormalities in schizophrenia patients
DA depletion | D2 occupancy | Radiotracer | Study | |
|---|---|---|---|---|
| Â | HC | SZ | Â | Â |
0.25 | 12% | 21% | [123I]IBZM | SPECT (Abi-Dargham et al. 2000) [22] |
0.20 | 26% | - | [123I]IBZM | SPECT (Laruelle et al. 1997) [34] |
0.29 | 13% | - | [18F]fallypride | PET (Riccardi et al. 2008) [36] |
0.29 | 22% | - | [11C]raclopride | PET (Verhoeff et al. 2001) [37] |
0.30 | - | 39% | [123I]IBZM | SPECT (Voruganti et al. 2001) [38] |