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Table 1 Striatal D2 receptor occupancies by DA estimated from receptor imaging studies.

From: Erratum to: Model-based parametric study of frontostriatal abnormalities in schizophrenia patients

DA depletion D2 occupancy Radiotracer Study
  HC SZ   
0.25 12% 21% [123I]IBZM SPECT (Abi-Dargham et al. 2000) [22]
0.20 26% - [123I]IBZM SPECT (Laruelle et al. 1997) [34]
0.29 13% - [18F]fallypride PET (Riccardi et al. 2008) [36]
0.29 22% - [11C]raclopride PET (Verhoeff et al. 2001) [37]
0.30 - 39% [123I]IBZM SPECT (Voruganti et al. 2001) [38]
  1. The value of DA depletion of 0.25, for example, corresponds to the depletion of 75% of endogenous DA.