Skip to main content

Table 2 RNFL thickness and macular thickness in different groups

From: Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients

Thickness (Mean ± SD) Bipolar disorder group Depression group Normal Control group F P/p (post-hoc) P′
Right RNFL
 Total thickness (μm) 90.69 ± 19.97 100.18 ± 14.12 102.13 ± 14.32 12.29 < 0.001/< 0.001a/0.593b/0.016c 0.004
 Superior thickness (μm) 110.34 ± 29.22 123.59 ± 23.53 120.13 ± 14.32 3.14 0.045/0.022a/0.607b/0.067c 0.017
 Inferior thickness (μm) 116.72 ± 33.32 122.05 ± 23.05 130.17 ± 22.37 6.75 0.001/< 0.001a/0.168b/0.401c 0.823
 Disc area (mm2) 2.35 ± 1.15 2.62 ± 0.63 2.34 ± 0.67 1.17 0.313 0.202
 Cup volume (mm3) 0.10 ± 0.12 0.26 ± 0.24 0.11 ± 0.13 11.55 < 0.001/0.697a/< 0.001bc 0.934
Left RNFL
 Total thickness (μm) 91.61 ± 14.85 97.27 ± 16.71 103.71 ± 11.94 19.73 < 0.001/< 0.001a/0.033b/0.084c 0.001
 Superior thickness (μm) 115.13 ± 25.36 129.95 ± 21.32 128.55 ± 22.51 8.12 < 0.001/< 0.001a/0.788b/0.01c 0.010
 Inferior thickness (μm) 119.13 ± 26.78 115.45 ± 34.02 133.88 ± 18.68 13.65 < 0.001/< 0.001ab/0.513c 0.010
 Disc area (mm2) 2.24 ± 1.17 2.32 ± 0.64 2.24 ± 0.57 0.11 0.899 0.224
 Cup volume (mm3) 0.08 ± 0.11 0.18 ± 0.12 0.11 ± 0.13 5.16 0.006/0.150a/0.011b/0.001c 0.252
Right macular (μm)
 Average thickness 255.24 ± 14.47 287.34 ± 26.01 263.82 ± 41.93 1.79 0.168 0.688
 Central thickness 220.06 ± 48.22 215.67 ± 25.45 227.03 ± 23.87 3.10 0.046 0.218
 Inner superior 273.49 ± 70.54 271.97 ± 71.62 302.54 ± 16.22 20.45 < 0.001/< 0.001ab/0.855c 0.001
 Inner inferior 263.52 ± 68.68 257.86 ± 70.50 293.47 ± 19.67 23.55 < 0.001/< 0.001ab/0.499 0.001
 Inner nasal 271.97 ± 71.02 271.03 ± 70.95 298.85 ± 30.97 13.33 < 0.001/< 0.001a/0.001b/0.921 0.001
 Inner temporal 262.11 ± 76.56 255.37 ± 66.42 287.27 ± 15.86 16.94 < 0.001/< 0.001ab/0.431 < 0.001
 Outer ring superior 246.61 ± 62.93 241.34 ± 63.01 267.60 ± 14.81 15.72 < 0.001/< 0.001ab/0.739 0.013
 Outer inferior 234.05 ± 61.13 236.46 ± 61.03 255.79 ± 15.11 13.73 < 0.001/< 0.001a/0.002b/0.739c 0.005
 Outer nasal 257.19 ± 65.72 257.49 ± 66.69 283.07 ± 16.44 17.69 < 0.001 < 0.001ab/0.970 0.002
 Outer temporal 225.22 ± 61.27 226.51 ± 58.73 248.99 ± 16.62 16.83 < 0.001/< 0.001ab0.858c 0.002
Left macular (μm)
 Average thickness 253.15 ± 48.47 266.40 ± 18.28 263.91 ± 36.37 2.53 0.081/0.033a/0.722b/0.097c 0.858
 Central thickness 221.58 ± 45.12 225.85 ± 28.21 224.19 ± 21.71 0.33 0.718 0.620
 Inner superior 285.56 ± 54.35 295.82 ± 20.27 302.96 ± 17.16 10.69 < 0.001/< 0.001a/0.177b/0.089c 0.038
 Inner inferior 274.90 ± 51.80 287.97 ± 28.25 292.06 ± 20.18 9.45 < 0.001/< 0.001a/0.456b/0.037c 0.515
 Inner nasal 286.60 ± 54.18 293.18 ± 27.48 298.44 ± 26.10 3.63 0.027/0.008a/0.396b/0.351c 0.700
 Inner temporal 270.56 ± 53.12 271.39 ± 25.46 282.70 ± 18.62 6.24 0.002/0.002a/0.037b/0.891c 0.081
 Outerring superior 248.63 ± 52.68 268.39 ± 16.24 267.11 ± 17.73 12.83 < 0.001/< 0.001a/0.804b/0.001c 0.096
 Outer inferior 241.28 ± 50.35 252.82 ± 21.51 255.43 ± 18.16 7.39 0.001/< 0.001a/0.610b/0.048c 0.094
 Outer nasal 264.64 ± 50.12 277.97 ± 23.37 279.0 ± 25.18 5.96 0.003/0.001a/0.859b/0.045c 0.174
 Outer temporal 235.64 ± 48.95 248.03 ± 18.28 247.96 ± 18.87 5.89 0.003/0.001a/0.989b/0.032c 0.605
  1. P′: adjusted p for analysis of covariance after controlling for smoker, ALT, AST, Glucose, Cholesterol, Triglyceride, Uric acid (left eye also controlling for left eye pressure) with Ancova
  2. P (post-hoc)
  3. acomparison between Bipolar disorder group and Normal Control group
  4. bcomparison between Depression group and Normal Control group
  5. ccomparison between Bipolar disorder group and Depression group
Back to article page

BMC Psychiatry

ISSN: 1471-244X

Contact us