Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients

BMC Psychiatry

Table 3 The factors related to RNFL and macular thickness in bipolar disorder patients^a,g

Right RNFL	Constant	Age of onset				UA				ALT
Right RNFL	Constant	ßl	S.E.	F1	P1	ß2	S.E.	F2	P2	ß3	S.E.	F3	P3
Total thickness (μm)	115.56	0.614	0.241	2.549	0.018
Superior thickness (μm)^b	64.02	1.070	0.384	2.787	0.010
Inferior thickness (μm)^c	284.81	0.820	0.403	2.037	0.054	0.180	0.072	2.488	0.021	−0.952	0.283	−3.358	0.003
Disc area (mm²)^d	−6.057	0.050	0.021	2.373	0.028
Right macular (μm)
Inner superior^e	269.46	−2.337	0.994	−2.351	0.027	−0.350	0.161	− 2.178	0.039	2.244	0.741	3.030	0.006
Inner inferior	307.51	−2.240	1.051	−2.131	0.044	−0.383	0.170	−2.255	0.034	1.195	0.783	2.548	0.018
Inner nasal^e	186.60	−1.943	0.983	−1.976	0.060	−0.043	0.155	−2.604	0.016
Inner temporal	290.80	−2.214	0.914	−2.323	0.029	−0.411	0.148	−2.782	0.010	1.926	0.681	2.829	0.009
Outer ring superior^e	145.50	−1.938	0.829	−2.339	0.028	−0.339	0.130	−2.605	0.016	1.528	0.647	2.363	0.027
Outer inferior^e	191.52	−1.711	0.855	−2.001	0.057	−0.277	0.138	−2.008	0.057	1.884	0.629	2.994	0.006
Outer nasal^e	126.94	−1.583	0.862	−1.838	0.080	−0.333	0.136	−2.444	0.023	1.408	0.673	2.093	0.048
Outer temporal^e	163.11	−1.737	0.869	−1.999	0.058	−0.364	0.137	−2.668	0.014	1.324	0.678	1.952	0.063
Left RNFL
Total thickness (μm)	116.03					−0.061	0.036	−1.705	0.099
Left macular
Inner superior	292.67									0.208	0.120	1.735	0.093
Inner inferior^f	313.12									0.239	0.108	2.219	0.034

ß: Beta of the multiple models, showing the variation of dependent variables (Y-axis) following an increase in the independent variable (X-axis)
ALT alanine aminotransferase, AST glutamic oxalacetic transaminase, UA uric acid, S.E Standard error
^aLinear regression with using smoker, age onset, sex, duration of illness (DOI), Family history, MAP, BMI, ALT, Glucose, Cholesterol, UA, FT3, eye pressure as independent variables
^bFT3 as covariates significantly in the equation
^cFamily history and MAP as covariates significantly in the equation
^dGlucose, BMI, Sex as covariates significantly in the equation
^eSmoker as a covariate significantly in the equation
^fSmoker and sex as covariates significantly in the equation
^gall the unlisted variables of retina above have no significant affective factors to enter the equation

ISSN: 1471-244X