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Table 3 The factors related to RNFL and macular thickness in bipolar disorder patientsa,g

From: Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients

Right RNFL Constant Age of onset UA ALT
ßl S.E. F1 P1 ß2 S.E. F2 P2 ß3 S.E. F3 P3
Total thickness (μm) 115.56 0.614 0.241 2.549 0.018         
Superior thickness (μm)b 64.02 1.070 0.384 2.787 0.010         
Inferior thickness (μm)c 284.81 0.820 0.403 2.037 0.054 0.180 0.072 2.488 0.021 −0.952 0.283 −3.358 0.003
Disc area (mm2)d −6.057 0.050 0.021 2.373 0.028         
Right macular (μm)
 Inner superiore 269.46 −2.337 0.994 −2.351 0.027 −0.350 0.161 − 2.178 0.039 2.244 0.741 3.030 0.006
 Inner inferior 307.51 −2.240 1.051 −2.131 0.044 −0.383 0.170 −2.255 0.034 1.195 0.783 2.548 0.018
 Inner nasale 186.60 −1.943 0.983 −1.976 0.060 −0.043 0.155 −2.604 0.016     
 Inner temporal 290.80 −2.214 0.914 −2.323 0.029 −0.411 0.148 −2.782 0.010 1.926 0.681 2.829 0.009
 Outer ring superiore 145.50 −1.938 0.829 −2.339 0.028 −0.339 0.130 −2.605 0.016 1.528 0.647 2.363 0.027
 Outer inferiore 191.52 −1.711 0.855 −2.001 0.057 −0.277 0.138 −2.008 0.057 1.884 0.629 2.994 0.006
 Outer nasale 126.94 −1.583 0.862 −1.838 0.080 −0.333 0.136 −2.444 0.023 1.408 0.673 2.093 0.048
 Outer temporale 163.11 −1.737 0.869 −1.999 0.058 −0.364 0.137 −2.668 0.014 1.324 0.678 1.952 0.063
Left RNFL
 Total thickness (μm) 116.03      −0.061 0.036 −1.705 0.099     
Left macular
 Inner superior 292.67          0.208 0.120 1.735 0.093
 Inner inferiorf 313.12          0.239 0.108 2.219 0.034
  1. ß: Beta of the multiple models, showing the variation of dependent variables (Y-axis) following an increase in the independent variable (X-axis)
  2. ALT alanine aminotransferase, AST glutamic oxalacetic transaminase, UA uric acid, S.E Standard error
  3. aLinear regression with using smoker, age onset, sex, duration of illness (DOI), Family history, MAP, BMI, ALT, Glucose, Cholesterol, UA, FT3, eye pressure as independent variables
  4. bFT3 as covariates significantly in the equation
  5. cFamily history and MAP as covariates significantly in the equation
  6. dGlucose, BMI, Sex as covariates significantly in the equation
  7. eSmoker as a covariate significantly in the equation
  8. fSmoker and sex as covariates significantly in the equation
  9. gall the unlisted variables of retina above have no significant affective factors to enter the equation