Factors related to retinal nerve fiber layer thickness in bipolar disorder patients and major depression patients

BMC Psychiatry

Table 4 The factors related to RNFL and macular thickness in major depression patients^a

Right RNFL	Constant	Age onset^b /duration of illness^c				CHO				ALT
Right RNFL	Constant	ßl	S.E.	F1	P1	ß2	S.E.	F2	P2	ß3	S.E.	F3	P3
Total thickness (μm)	86.34	−0.602	0.282	−2.185	0.059^b
Inferior thickness (μm)	−25.28	−1.268	0.574	−2.211	0.058^b	26.62	9.232	2.884	0.020
Right macular (μm)
Average thickness ^d	352.80	0.630	0.293	2.155	0.050^b	−13.204	5.203	−2.538	0.020
Inner superior	312.09									−1.094	0.499	− 2.191	0.042
Ourter superior	277.77									−1.042	0.432	−2.410	0.027
Outer inferior	270.70									−0.995	0.422	−2.357	0.030
Left RNFL
Total thickness (μm)^e	−68.81	− 0.145	0.019	−7.532	0.002^c	17.438	2.835	6.152	0.004
Inferior thickness (μm)^f	−170.57	−0.249	0.044	−5.655	0.002^c	28.310	6.264	4.519	0.006
Disc area (mm²)^g	8.805	−0.033	0.008	−4.322	0.023
Cup volume (mm³)^h	−0.874	−0.002		−8.904	< 0.001^c					0.008	0.001	8.261	< 0.001
Left macular (μm)
Inner superior	284.25	0.366	0.143	2.560	0.020^b
Inner inferior
Inner nasal	279.40									0.440	0.193	2.278	0.036
Inner temporal	261.01									0.396	0.168	2.354	0.031
Ourter superior	222.29	−0.104	0.048	−2.166	0.047^c

^a linear regression with using smoker, age onset, sex, duration of illness, BMI, MAP, ALT, Glucose, Cholesterol, UA, FT3, as independent variables
ALT alanine aminotransferase, AST glutamic oxalacetic transaminase, UA uric acid, CHO Cholesterol, S.E Standard error
^bAge onset
^cDuration of illness
^dUA as covariates significantly in the equation
^eSmoker, Sex, BMI,MAP, FT3,Glucose as covariates significantly in the equation
^fSex, BMI,BMP, FT3,Glucose as covariates significantly in the equation
^gSex, FT3,UA, Glucose as covariates significantly in the equation
^hSmoker, Sex,MAP, Glucose as covariates significantly in the eq
ⁱBMI as covariates significantly in the equation

ISSN: 1471-244X