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Table 3 Findings of subgroup analyses based on sensitivity, specificity, and AUC for MMSE

From: A systematic review and meta-analysis of studies on screening for mild cognitive impairment in primary healthcare

  No. of studies Pooled Estimates [95% CI] I2 p-Value for Heterogeneity Tau-Squared
Sensitivity
Age (year)
  ≥ 75 3 0.71 (0.53–0.88) 99.8  < 0.001 0.67
   < 75 3 0.76 (0.46–1.05) 94.9  < 0.001 0.03
Sample size
   > 1000 2 0.72 (0.30–1.13) 99.9  < 0.001 0.08
   ≤ 1000 5 0.74 (0.64–0.89) 93.2  < 0.001 0.01
Country’s income
  High income 5 0.56 (0.48–0.83) 98.1  < 0.001 0.0379
  Low income 2 0.91 (0.89–0.94) 69.1  < 0.001 0.0003
Specificity
Age (year)
   ≥ 75 3 0.81 (0.67–0.95) 93.9  < 0.001 0.018
   < 75 3 0.84 (0.58–1.09) 99.1  < 0.001 0.035
Sample size
   > 1000 2 0.97 (0.96–0.97) 0  < 0.001 0
   ≤ 1000 5 0.79(0.65–0.93) 96.7  < 0.001 0.023
AUC
Age (year)
   ≥ 75 5 0.73(0.67–0.80) 0  < 0.001 0
   < 75 2 0.95 (0.90–1.00) 98.3  < 0.001 0.001
Sample size
   > 1000 2 0.97 (0.97–0.98) 98.3  < 0.001 0.01
   ≤ 1000 5 0.73 (0.65–0.86) 0  < 0.001 0
Country’s income
  High income 5 0.79 (0.64–0.94) 97.6  < 0.001 0.027
  Low income 2 0.96 (0.94–0.98) 0  < 0.001 0