Table 3 Findings of subgroup analyses based on sensitivity, specificity, and AUC for MMSE
No. of studies | Pooled Estimates [95% CI] | I2 | p-Value for Heterogeneity | Tau-Squared | |
|---|---|---|---|---|---|
Sensitivity | |||||
Age (year) | |||||
≥ 75 | 3 | 0.71 (0.53–0.88) | 99.8 | < 0.001 | 0.67 |
< 75 | 3 | 0.76 (0.46–1.05) | 94.9 | < 0.001 | 0.03 |
Sample size | |||||
> 1000 | 2 | 0.72 (0.30–1.13) | 99.9 | < 0.001 | 0.08 |
≤ 1000 | 5 | 0.74 (0.64–0.89) | 93.2 | < 0.001 | 0.01 |
Country’s income | |||||
High income | 5 | 0.56 (0.48–0.83) | 98.1 | < 0.001 | 0.0379 |
Low income | 2 | 0.91 (0.89–0.94) | 69.1 | < 0.001 | 0.0003 |
Specificity | |||||
Age (year) | |||||
≥ 75 | 3 | 0.81 (0.67–0.95) | 93.9 | < 0.001 | 0.018 |
< 75 | 3 | 0.84 (0.58–1.09) | 99.1 | < 0.001 | 0.035 |
Sample size | |||||
> 1000 | 2 | 0.97 (0.96–0.97) | 0 | < 0.001 | 0 |
≤ 1000 | 5 | 0.79(0.65–0.93) | 96.7 | < 0.001 | 0.023 |
AUC | |||||
Age (year) | |||||
≥ 75 | 5 | 0.73(0.67–0.80) | 0 | < 0.001 | 0 |
< 75 | 2 | 0.95 (0.90–1.00) | 98.3 | < 0.001 | 0.001 |
Sample size | |||||
> 1000 | 2 | 0.97 (0.97–0.98) | 98.3 | < 0.001 | 0.01 |
≤ 1000 | 5 | 0.73 (0.65–0.86) | 0 | < 0.001 | 0 |
Country’s income | |||||
High income | 5 | 0.79 (0.64–0.94) | 97.6 | < 0.001 | 0.027 |
Low income | 2 | 0.96 (0.94–0.98) | 0 | < 0.001 | 0 |