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  1. The aim of present study is to measure plasma clozapine (CLZ) and N-desmethyl clozapine (DMC) as biomarkers to correlate drug concentrations with the appearance of preclinical adverse hematic effects.

    Authors: Mayela Vaquero-Baez, Araceli Díaz-Ruíz, Luis Tristán-López, Carlos Aviña-Cervantes, Carlos Torner, Jesús Ramírez-Bermúdez, Sergio Montes and Camilo Ríos

    Citation: BMC Psychiatry 2019 19:295

    Content type: Research article

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  2. Research can inform culturally-appropriate care to strengthen social and emotional wellbeing (SEWB) among Aboriginal and Torres Strait Islander (hereafter, the term ‘Indigenous Peoples’ is respectfully used an...

    Authors: Sara Farnbach, Graham Gee, Anne-Marie Eades, John Robert Evans, Jamie Fernando, Belinda Hammond, Matty Simms, Karrina DeMasi and Maree L. Hackett

    Citation: BMC Psychiatry 2019 19:294

    Content type: Research article

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  3. Schizophrenia is a severe mental disease with high morbidity and heritability. The SLC39A8 gene is located in 4q24 and encodes a protein that transports many metal ions. Multiple previous studies found that one o...

    Authors: Xuemin Jian, Jianhua Chen, Zhiqiang Li, Zhijian Song, Juan Zhou, Wei Xu, Yahui Liu, Jiawei Shen, Yonggang Wang, Qizhong Yi and Yongyong Shi

    Citation: BMC Psychiatry 2019 19:293

    Content type: Research article

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  4. Women with bipolar disorder (BD) have a high risk of illness relapse postpartum. The risk coincides with the period when mother-infant interactions are evolving. We compared mother-infant interactions in dyads...

    Authors: Teija M. S. Anke, Kari Slinning, Vibeke Moe, Cathrine Brunborg, Torill S. Siqveland and Dag Vegard Skjelstad

    Citation: BMC Psychiatry 2019 19:292

    Content type: Research article

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  5. The Patient Health Questionnaire-9 (PHQ-9) is a brief tool to assess the presence and severity of depressive symptoms. This study aimed to validate and calibrate the PHQ-9 to determine appropriate cut-off poin...

    Authors: María Urtasun, Federico Manuel Daray, Germán Leandro Teti, Fernando Coppolillo, Gabriela Herlax, Guillermo Saba, Adolfo Rubinstein, Ricardo Araya and Vilma Irazola

    Citation: BMC Psychiatry 2019 19:291

    Content type: Research article

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  6. Meta-analyses of randomised controlled trials suggest that psychological interventions to reduce children’s risk of depression are effective. Nevertheless, these effects are modest and diminish over time. The ...

    Authors: Nathalie Claus, Lisa Marzano, Johanna Loechner, Kornelija Starman, Alessandra Voggt, Fabian Loy, Inga Wermuth, Stephanie Haemmerle, Lina Engelmann, Mirjam Bley, Gerd Schulte-Koerne and Belinda Platt

    Citation: BMC Psychiatry 2019 19:290

    Content type: Research article

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  7. While postpartum depression is a well-researched disorder in mothers, there is growing evidence indicating that some fathers also develop depressive symptoms (paternal postpartum depression, PPD). A recent met...

    Authors: Julia Albicker, Lars P. Hölzel, Jürgen Bengel, Katharina Domschke, Levente Kriston, Miriam A. Schiele and Fabian Frank

    Citation: BMC Psychiatry 2019 19:289

    Content type: Study protocol

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  8. Common mental disorders such as depression and anxiety frequently co-occur and may share etiological mechanisms. The metacognitive model is based on the principle that there are common pathological mechanisms ...

    Authors: Henrik Nordahl, Ingunn Harsvik Ødegaard, Odin Hjemdal and Adrian Wells

    Citation: BMC Psychiatry 2019 19:288

    Content type: Research article

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  9. Cardiovascular disease (CVD) is the leading cause of premature death among people with serious mental illness (SMI). Sedentary behaviour (SB) is an independent risk factor for CVD and mortality and people with...

    Authors: Julie Williams, Brendon Stubbs, Sol Richardson, Cathy Flower, Lucy Barr-Hamilton, Barbara Grey, Kathryn Hubbard, Gilda Spaducci, Fiona Gaughran and Tom Craig

    Citation: BMC Psychiatry 2019 19:287

    Content type: Research article

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  11. Major depressive disorder is one of the most prevalent and disabling forms of mental illness in the general population. One public health strategy that may reduce the disease burden is early identification and...

    Authors: JianLi Wang, Glenda MacQueen, Scott Patten, Douglas Manuel, Bonnie Lashewicz and Norbert Schmitz

    Citation: BMC Psychiatry 2019 19:285

    Content type: Study protocol

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  12. Among patients suffering from coronary heart disease (CHD) and comorbid depression, women experience a higher burden compared to men. Little is known on the characteristics that differentiate men and women wit...

    Authors: Hala Allabadi, Nicole Probst-Hensch, Abdulsalam Alkaiyat, Saleem Haj-Yahia, Christian Schindler, Marek Kwiatkowski and Elisabeth Zemp

    Citation: BMC Psychiatry 2019 19:284

    Content type: Research article

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  13. Harmful use of alcohol is a global public health problem. Differences in alcohol consumption patterns may add valuable information to the design of public health interventions to prevent excessive use of alcoh...

    Authors: Tara Ballav Adhikari, Anupa Rijal, Per Kallestrup and Dinesh Neupane

    Citation: BMC Psychiatry 2019 19:283

    Content type: Research article

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  14. Prepulse inhibition (PPI) is a measurement method for the sensory gating process, which helps the brain adapt to complex environments. PPI may be reduced in patients with bipolar disorder (BD). This study inve...

    Authors: Zhen Mao, Qijing Bo, Weidi Li, Zhimin Wang, Xin Ma and Chuanyue Wang

    Citation: BMC Psychiatry 2019 19:282

    Content type: Research article

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  15. Prodynorphin (PDYN) gene polymorphisms have been linked with opioid dependence (OD) with conflicting outcomes, the aim of this study is to synthesize the existing evidence of the association between PDYN polymorp...

    Authors: Chang-wang Wang, Min Ma, Wei-guang Lu and Ru-qin Luo

    Citation: BMC Psychiatry 2019 19:281

    Content type: Research article

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  16. Personality Disorder (PD) is an enduring, multi-faceted mental disorder, associated with adverse health effects, difficulties with interpersonal relationships and in some cases increased risk to others. A limi...

    Authors: Zoe Foyston, Celia Taylor and Mark Freestone

    Citation: BMC Psychiatry 2019 19:280

    Content type: Research article

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  17. Maternal mental health is an international public health concern. Many women experience mental ill-health during and after pregnancy, but assessment is not part of routine maternity care in many low- and middl...

    Authors: Mary McCauley, Abigail Brown, Bernice Ofosu and Nynke van den Broek

    Citation: BMC Psychiatry 2019 19:279

    Content type: Research article

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    The Correction to this article has been published in BMC Psychiatry 2019 19:304

  18. People in green professions are exposed to a variety of risk factors, which could possibly enhance the development of depression. Amongst possible prevention approaches, internet- and mobile-based intervention...

    Authors: Lina Braun, Ingrid Titzler, David Daniel Ebert, Claudia Buntrock, Yannik Terhorst, Johanna Freund, Janika Thielecke and Harald Baumeister

    Citation: BMC Psychiatry 2019 19:278

    Content type: Study protocol

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  19. The screening of digital footprint for clinical purposes relies on the capacity of wearable technologies to collect data and extract relevant information’s for patient management. Artificial intelligence (AI) ...

    Authors: Sofian Berrouiguet, María Luisa Barrigón, Jorge Lopez Castroman, Philippe Courtet, Antonio Artés-Rodríguez and Enrique Baca-García

    Citation: BMC Psychiatry 2019 19:277

    Content type: Study protocol

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  21. Suicide has profound effects on families and communities, but is a statistically rare event. Psychological autopsies using a case-control design allow researchers to examine risk factors for suicide, using a v...

    Authors: E. Arensman, C. Larkin, J. McCarthy, S. Leitao, P. Corcoran, E. Williamson, C. McAuliffe, I. J. Perry, E. Griffin, E. M. Cassidy, C. Bradley, N. Kapur, J. Kinahan, A. Cleary, T. Foster, J. Gallagher…

    Citation: BMC Psychiatry 2019 19:275

    Content type: Technical advance

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  22. Intracranial arachnoid cysts are usually benign congenital findings of neuroimaging modalities, sometimes however, leading to focal neurological and psychiatric comorbidities. Whether primarily clinically sile...

    Authors: Anna-Sophia Wahl, Martin Löffler, Lucrezia Hausner, Michaela Ruttorf, Frauke Nees and Lutz Frölich

    Citation: BMC Psychiatry 2019 19:274

    Content type: Case report

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  23. Many Canadian adolescents and young adults with mental health problems face delayed detection, long waiting lists, poorly accessible services, care of inconsistent quality and abrupt or absent inter-service tr...

    Authors: Srividya N. Iyer, Jai Shah, Patricia Boksa, Shalini Lal, Ridha Joober, Neil Andersson, Rebecca Fuhrer, Amal Abdel-Baki, Ann M. Beaton, Paula Reaume-Zimmer, Daphne Hutt-MacLeod, Mary Anne Levasseur, Ranjith Chandrasena, Cécile Rousseau, Jill Torrie, Meghan Etter…

    Citation: BMC Psychiatry 2019 19:273

    Content type: Study protocol

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  24. Problems in social functioning (e.g., unemployment, social isolation), are common in people with a psychotic disorder. Social cognition is a treatment target to improve social functioning, as it is a proximal ...

    Authors: Saskia A. Nijman, Wim Veling, Kirstin Greaves-Lord, Rowina R. Vermeer, Maarten Vos, Catharina E. R. Zandee, Daniëlle C. Zandstra, Chris N. W. Geraets and Gerdina H. M. Pijnenborg

    Citation: BMC Psychiatry 2019 19:272

    Content type: Study protocol

    Published on:

  25. The increasing elderly population worldwide is likely to increase mental health problems such as geriatric depression, which has mostly been studied in high-income countries. Similar studies are scarce in low-...

    Authors: Kedar Manandhar, Ajay Risal, Oshin Shrestha, Nirmala Manandhar, Dipak Kunwar, Rajendra Koju and Are Holen

    Citation: BMC Psychiatry 2019 19:271

    Content type: Research article

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  26. The treatment of homeless dual-diagnosis patients (i.e., those with severe mental illness and substance-use disorder) is difficult and often fails. For patients in the Netherlands who had not responded to earl...

    Authors: G. D. van Kranenburg, R. H. S. van den Brink, W. G. Mulder, W. J. Diekman, G. H. M. Pijnenborg and C. L. Mulder

    Citation: BMC Psychiatry 2019 19:270

    Content type: Research article

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  27. Although the adverse effects of cancer diagnoses and treatments on mental health are known, about less than 10% of patients are estimated to be referred to seek help. The primary purpose of this study was to o...

    Authors: Dilek Anuk, Mine Özkan, Ahmet Kizir and Sedat Özkan

    Citation: BMC Psychiatry 2019 19:269

    Content type: Research article

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  28. Family and friends (carer) involvement in the treatment of people with mental illness is widely recommended. However, the implementation remains poor, especially during hospital treatment, where carers report ...

    Authors: Justina Kaselionyte, Maev Conneely and Domenico Giacco

    Citation: BMC Psychiatry 2019 19:268

    Content type: Research article

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  29. The goal of clinicians and healthcare workers providing treatment to patients with psychiatric disorders, has shifted over time from focusing on the symptoms alone towards functional improvement. In this study...

    Authors: Xiao Wei Tan, Esmond Seow, Edimansyah Abdin, Swapna Verma, Kang Sim, Siow Ann Chong and Mythily Subramaniam

    Citation: BMC Psychiatry 2019 19:267

    Content type: Research article

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  30. Although massive studies have explored the risk factors of suicidal ideation (SI), the prevalence of SI and its associated factors in the hypertensive individuals are largely unknown. This study aims to invest...

    Authors: Dandan Ge, Xinyi Zhang, Xiaolei Guo, Jie Chu, Long Sun and Chengchao Zhou

    Citation: BMC Psychiatry 2019 19:266

    Content type: Research article

    Published on:

  31. Several international guidelines for the acute treatment of moderate to severe unipolar depression recommend a first-line treatment with antidepressants (AD). This is based on the assumption that AD obviously ...

    Authors: Martin Plöderl and Michael P. Hengartner

    Citation: BMC Psychiatry 2019 19:265

    Content type: Debate

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  32. The terms affective dysregulation (AD) and irritability describe transdiagnostic dimensions and are characterized by an excessive reactivity to negative emotional stimuli with an affective (anger) and a behavi...

    Authors: Manfred Döpfner, Josepha Katzmann, Charlotte Hanisch, Jörg M. Fegert, Michael Kölch, Anne Ritschel, Anne-Katrin Treier, Martin Hellmich, Veit Roessner, Ulrike Ravens-Sieberer, Tobias Banaschewski and Anja Görtz-Dorten

    Citation: BMC Psychiatry 2019 19:264

    Content type: Study protocol

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  33. This study examined the effects of the standard model of family psychoeducation (SM-FPE) in Japan on the mental health of relatives who care for young patients with a psychotic disorder.

    Authors: Nao Shiraishi, Norio Watanabe, Fujika Katsuki, Hajime Sakaguchi and Tatsuo Akechi

    Citation: BMC Psychiatry 2019 19:263

    Content type: Research article

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  34. Clear guidance for successive antidepressant pharmacological treatments for non-responders in major depression is not well established.

    Authors: D. Bennabi, T. Charpeaud, A. Yrondi, J.-B. Genty, S. Destouches, S. Lancrenon, N. Alaïli, F. Bellivier, T. Bougerol, V. Camus, J.-M. Dorey, O. Doumy, F. Haesebaert, J. Holtzmann, C. Lançon, M. Lefebvre…

    Citation: BMC Psychiatry 2019 19:262

    Content type: Research article

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  35. Few studies exploring the actual practices implemented for long-term mental health and psychosocial support after a natural disaster have been published. This study aimed to reveal (1) the types of activities ...

    Authors: Moe Seto, Harumi Nemoto, Natsuko Kobayashi, Saya Kikuchi, Nami Honda, Yoshiharu Kim, Ilan Kelman and Hiroaki Tomita

    Citation: BMC Psychiatry 2019 19:261

    Content type: Research article

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  36. Functional somatic symptoms in depression disorder may cause inappropriate illness behavior hindering the treatment process. Health anxiety may play a role in this relationship, but few studies have examined i...

    Authors: Yue-Jiao Ma, Dong-Fang Wang, Ming Yuan, Jiang Long, Shu-Bao Chen, Qiu-Xia Wu, Xu-Yi Wang and Tie-Qiao Liu

    Citation: BMC Psychiatry 2019 19:260

    Content type: Research article

    Published on:

  37. Antenatal depression is a prevalent mental disorder in women who have undergone caesarean section, and it often presages adverse postoperative outcomes. Because of the lack of a laboratory-based diagnostic str...

    Authors: Zhuoxi Wu, Peng Zhao, Zhonghong Long, Jie Li, Guiying Yang, Qingling Zhang, Guangyou Duan and Hong Li

    Citation: BMC Psychiatry 2019 19:259

    Content type: Research article

    Published on:

  38. Diabetes is a highly prevalent non-communicable disease which is prone to more psychiatric complications like suicide; however, research into this area is limited. Assessing suicidal plan and attempt as well a...

    Authors: Mogesie Necho, Solomon Mekonnen, Kelemua Haile, Mengesha Birkie and Asmare Belete

    Citation: BMC Psychiatry 2019 19:258

    Content type: Research article

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  39. The behavioral health service provider population is highly heterogeneous. However, it is rarely treated as such within evidence-based practice implementation efforts. This study aimed to evaluate, as a proof ...

    Authors: Emily M. Becker-Haimes, Viktor Lushin, Torrey A. Creed and Rinad S. Beidas

    Citation: BMC Psychiatry 2019 19:257

    Content type: Research article

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  40. Despite the rising recognition of personal recovery, there is a lack of research on personal recovery in individuals with psychosis in Singapore. This study aims to evaluate the psychometric properties of the ...

    Authors: Madeline Lim, Ziqiang Li, Huiting Xie, Bhing Leet Tan and Jimmy Lee

    Citation: BMC Psychiatry 2019 19:256

    Content type: Research article

    Published on:

  41. With the advent of the recovery movement in mental health, a humanistic paradigm shift has occurred, placing the focus on personal recovery (i.e., hope, identity, and life meaning) instead of functional or clinic...

    Authors: Sunny H. W. Chan, Samson Tse, K. F. Chung, C. H. Yu, Raymond C. K. Chung and Herman H. M. Lo

    Citation: BMC Psychiatry 2019 19:255

    Content type: Study protocol

    Published on:

  42. To measure the serum levels of brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) in deficit schizophrenia (DS), in order to examine the association between these t...

    Authors: Xiaowei Tang, Chao Zhou, Ju Gao, Weiwei Duan, Miao Yu, Wenhuan Xiao, Xiaobin Zhang, Hui Dong, Xiang Wang and Xiangrong Zhang

    Citation: BMC Psychiatry 2019 19:254

    Content type: Research article

    Published on:

  43. Suicide is a serious public health concern. Depression is the main gateway to suicidal behavior. The already established relationship between depression and suicidal risk should now focus on the investigation ...

    Authors: Miquel Roca, Antonio Riera-López del Amo, Pau Riera-Serra, Mª. Angeles Pérez-Ara, Adoración Castro, J. Roman Juan, Mauro García-Toro, Patricia García-Pazo and Margalida Gili

    Citation: BMC Psychiatry 2019 19:253

    Content type: Study protocol

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  44. This commentary examines publicly available information on 2017–2018 outcomes in the UK government’s Improving Access to Psychological Therapies (IAPT) programme, a National Health Service (NHS) primary care m...

    Authors: Naomi Petra Moller, Gemma Ryan, Jasmine Rollings and Michael Barkham

    Citation: BMC Psychiatry 2019 19:252

    Content type: Correspondence

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    The Correction to this article has been published in BMC Psychiatry 2019 19:302

  45. Therapeutic staff-patient interaction is fundamental in psychiatric care. It is recognized as a key to healing in and of itself, or a premise to enhance psychiatric treatment adherence. Still, little is known ...

    Authors: Kjellaug K. Myklebust and Stål Bjørkly

    Citation: BMC Psychiatry 2019 19:251

    Content type: Research article

    Published on:

  46. National Institute of alcohol and alcoholism define Problem/risky use of alcohol as drinking in a way that can negatively impact our health and life, but the body is not physically dependent on the substance. ...

    Authors: Abate Dargie Wubetu, Surafel Habte and Kefyalew Dagne

    Citation: BMC Psychiatry 2019 19:250

    Content type: Research article

    Published on:

  47. Mental illnesses among children and adolescents are under-recognized and under-treated problems. Depression is one of today’s all-too-silent health crises in caregivers. Although primary caregivers of children...

    Authors: Woredaw Minichil, Wondale Getinet, Habtamu Derajew and Sofia Seid

    Citation: BMC Psychiatry 2019 19:249

    Content type: Research article

    Published on:

  48. Major mental disorders in prison populations have been recognised as a long-term problem with an important impact on public health. Despite this, screening activities in prisons are still weak in Latin America...

    Authors: Andrés Benavides, Juan Chuchuca, David Klaic, William Waters, Miguel Martín and Natalia Romero-Sandoval

    Citation: BMC Psychiatry 2019 19:248

    Content type: Research article

    Published on:

  50. Depression is a major problem among nurses; hence, it is important to develop a primary prevention strategy to manage depression among nurses. This randomized controlled trial (RCT) study aims to investigate t...

    Authors: Kazuto Kuribayashi, Kotaro Imamura, Kazuhiro Watanabe, Yuki Miyamoto, Ayumi Takano, Utako Sawada, Natsu Sasaki, Mariko Suga, Atsushi Sugino, Yui Hidaka, Mako Iida, Mie Sudo, Masahito Tokita and Norito Kawakami

    Citation: BMC Psychiatry 2019 19:245

    Content type: Study protocol

    Published on:

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