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  1. Although much progress has been made on antipsychotic drug development, precise mechanisms behind the action of typical and atypical antipsychotics are poorly understood.

    Authors: Kwang H Choi, Brandon W Higgs, Serge Weis, Jonathan Song, Ida C Llenos, Jeannette R Dulay, Robert H Yolken and Maree J Webster
    Citation: BMC Psychiatry 2009 9:57
  2. A proportion of people with mental health problems require longer term care in a psychiatric or social care institution. However, there are no internationally agreed quality standards for institutional care an...

    Authors: Tatiana L Taylor, Helen Killaspy, Christine Wright, Penny Turton, Sarah White, Thomas W Kallert, Mirjam Schuster, Jorge A Cervilla, Paulette Brangier, Jiri Raboch, Lucie Kališová, Georgi Onchev, Hristo Dimitrov, Roberto Mezzina, Kinou Wolf, Durk Wiersma…
    Citation: BMC Psychiatry 2009 9:55
  3. Switching between antipsychotic medications is common in the treatment of schizophrenia. However, data on clinical and economic outcomes from antipsychotic switching, in particular acute care service use, is f...

    Authors: Douglas E Faries, Haya Ascher-Svanum, Allen W Nyhuis and Bruce J Kinon
    Citation: BMC Psychiatry 2009 9:54
  4. Prior research has shown a higher prevalence of substance use and mental disorders among sexual minorities, however, the influence of sexual orientation on treatment seeking has not been widely studied. We use...

    Authors: Christine E Grella, Lisa Greenwell, Vickie M Mays and Susan D Cochran
    Citation: BMC Psychiatry 2009 9:52
  5. Case registers have been used extensively in mental health research. Recent developments in electronic medical records, and in computer software to search and analyse these in anonymised format, have the poten...

    Authors: Robert Stewart, Mishael Soremekun, Gayan Perera, Matthew Broadbent, Felicity Callard, Mike Denis, Matthew Hotopf, Graham Thornicroft and Simon Lovestone
    Citation: BMC Psychiatry 2009 9:51
  6. Bipolar disorders affect between 3–5% of the population and are associated with considerable lifelong impairment. Since much of the morbidity associated with bipolar disorder is caused by recurrent depressive ...

    Authors: Sharon Simpson, Emma Barnes, Emily Griffiths, Kerry Hood, David Cohen, Nick Craddock, Ian Jones and Daniel J Smith
    Citation: BMC Psychiatry 2009 9:50
  7. Substance use disorders have repeatedly been found to lead to premature death, i.e. drug-related death by disease, fatal intoxications, or trauma (accidents, suicide, undetermined suicide, and homicide). The p...

    Authors: Louise Brådvik, Mats Berglund, Arne Frank, Anna Lindgren and Peter Löwenhielm
    Citation: BMC Psychiatry 2009 9:48
  8. Ethnic minority groups are under-represented in mental health care services because of barriers such as poor mental health literacy. In 2007, the Mental Health First Aid (MHFA) program implemented a cultural a...

    Authors: Laura M Hart, Anthony F Jorm, Leonard G Kanowski, Claire M Kelly and Robyn L Langlands
    Citation: BMC Psychiatry 2009 9:47
  9. Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediatel...

    Authors: Haya Ascher-Svanum, Xiaomei Peng, Douglas Faries, William Montgomery and Peter M Haddad
    Citation: BMC Psychiatry 2009 9:46
  10. Hungary previously had one of the highest suicide rates in the world, but experienced major social and economic changes from 1990 onwards. We aimed to investigate the antecedents of suicide in Hungary. We hypo...

    Authors: Kitty Almasi, Nora Belso, Navneet Kapur, Roger Webb, Jayne Cooper, Sarah Hadley, Michael Kerfoot, Graham Dunn, Peter Sotonyi, Zoltan Rihmer and Louis Appleby
    Citation: BMC Psychiatry 2009 9:45
  11. Neurocognitive impairment and psychiatric symptoms have been associated with deficits in psychosocial and occupational functioning in patients with schizophrenia. This post-hoc analysis evaluates the relations...

    Authors: Ilya A Lipkovich, Walter Deberdt, John G Csernansky, Bernard Sabbe, Richard SE Keefe and Sara Kollack-Walker
    Citation: BMC Psychiatry 2009 9:44
  12. There is an ongoing debate on whether consumers of child pornography pose a risk for hands-on sex offenses. Up until now, there have been very few studies which have analyzed the association between the consum...

    Authors: Jérôme Endrass, Frank Urbaniok, Lea C Hammermeister, Christian Benz, Thomas Elbert, Arja Laubacher and Astrid Rossegger
    Citation: BMC Psychiatry 2009 9:43
  13. The Brief Fear of Negative Evaluation Scale (BFNE) is a commonly used instrument to measure social anxiety. This study aimed to translate and to test the reliability and validity of the BFNE in Iran.

    Authors: Azadeh Tavoli, Mahdiyeh Melyani, Maryam Bakhtiari, Gholam Hossein Ghaedi and Ali Montazeri
    Citation: BMC Psychiatry 2009 9:42
  14. Crises and (involuntary) admissions have a strong impact on patients and their caregivers. In some countries, including the Netherlands, the number of crises and (involuntary) admissions have increased in the ...

    Authors: A Ruchlewska, CL Mulder, R Smulders, BJ Roosenschoon, G Koopmans and A Wierdsma
    Citation: BMC Psychiatry 2009 9:41
  15. Many students who begin university at risky periods for OCD development cannot meet the new challenges successfully. They often seek help and apply to the university health center for psychiatric distress. We ...

    Authors: Elcin Yoldascan, Yarkin Ozenli, Oguz Kutlu, Kenan Topal and Ali Ihsan Bozkurt
    Citation: BMC Psychiatry 2009 9:40
  16. Adherence has recently been suggested to be divided into these two components: persistence (i.e., whether patients continue treatment or not) and compliance (i.e., whether patients take doses as instructed). H...

    Authors: Norifusa Sawada, Hiroyuki Uchida, Takefumi Suzuki, Koichiro Watanabe, Toshiaki Kikuchi, Takashi Handa and Haruo Kashima
    Citation: BMC Psychiatry 2009 9:38
  17. Psychiatric disorders affect about 450 million individuals worldwide. A number of treatment modalities such as psychotropic medications, psychotherapy and electroconvulsive therapy can be used to treat these d...

    Authors: Abdul Mueed Zafar, Ali Jawaid, Hiba Ashraf, Ambreena Fatima, Rubina Anjum and Salah U Qureshi
    Citation: BMC Psychiatry 2009 9:37
  18. This study aims to build a measure for assessing and reviewing the living conditions, care and human rights of people with longer term mental health problems in psychiatric and social care institutions. Protec...

    Authors: Helen Killaspy, Michael King, Christine Wright, Sarah White, Paul McCrone, Thomas Kallert, Jorge Cervilla, Jiri Raboch, Georgi Onchev, Roberto Mezzina, Durk Wiersma, Andrzej Kiejna, Dimitris Ploumpidis and José Miguel Caldas de Almeida
    Citation: BMC Psychiatry 2009 9:36
  19. Individuals with autism spectrum disorders (ASDs) often display symptoms from other diagnostic categories. Studies of clinical and psychosocial outcome in adult patients with ASDs without concomitant intellect...

    Authors: Björn Hofvander, Richard Delorme, Pauline Chaste, Agneta Nydén, Elisabet Wentz, Ola Ståhlberg, Evelyn Herbrecht, Astrid Stopin, Henrik Anckarsäter, Christopher Gillberg, Maria Råstam and Marion Leboyer
    Citation: BMC Psychiatry 2009 9:35
  20. violence is a public health major concern, and it is associated with post-traumatic stress disorder and other psychiatric outcomes. Brazil is one of the most violent countries in the world, and has an extreme ...

    Authors: Sérgio Baxter Andreoli, Wagner Silva Ribeiro, Maria Ines Quintana, Camila Guindalini, Gerome Breen, Sergio Luis Blay, Evandro SF Coutinho, Trudy Harpham, Miguel Roberto Jorge, Diogo Rizzato Lara, Tais S Moriyama, Lucas C Quarantini, Ary Gadelha, Liliane Maria Pereira Vilete, Mary SL Yeh, Martin Prince…
    Citation: BMC Psychiatry 2009 9:34
  21. To describe the clinical course and treatment patterns over 24 months of patients experiencing an acute manic/mixed episode within the standard course of care.

    Authors: Jean-Michel Azorin, Elodie Aubrun, Jordan Bertsch, Catherine Reed, Stephanie Gerard and Michael Lukasiewicz
    Citation: BMC Psychiatry 2009 9:33
  22. Family history of suicide attempt is one of the risks of suicide. We aimed at exploring the characteristics of Japanese suicide attempters with and without a family history of suicide attempt.

    Authors: Makiko Nakagawa, Chiaki Kawanishi, Tomoki Yamada, Yoko Iwamoto, Ryoko Sato, Hana Hasegawa, Satoshi Morita, Toshinari Odawara and Yoshio Hirayasu
    Citation: BMC Psychiatry 2009 9:32
  23. Clinical evidence has long suggested there may be heterogeneity in the patterns and predictors of common mood and anxiety disorders; however, epidemiologic studies have generally treated these outcomes as homo...

    Authors: Arijit Nandi, John R Beard and Sandro Galea
    Citation: BMC Psychiatry 2009 9:31
  24. Life trauma is highly prevalent in the general population and posttraumatic stress disorder is among the most prevalent psychiatric consequences of trauma exposure. Brazil has a unique environment to conduct t...

    Authors: Rodrigo A Bressan, Lucas C Quarantini, Sérgio B Andreoli, Celia Araújo, Gerome Breen, Camila Guindalini, Marcelo Hoexter, Andrea P Jackowski, Miguel R Jorge, Acioly LT Lacerda, Diogo R Lara, Stella Malta, Tais S Moriyama, Maria I Quintana, Wagner S Ribeiro, Juliana Ruiz…
    Citation: BMC Psychiatry 2009 9:30
  25. One in nine American women will meet criteria for the diagnosis of posttraumatic stress disorder (PTSD) in their lifetime. Although twin studies suggest genetic influences account for substantial variance in P...

    Authors: Karestan C Koenen, Immaculata De Vivo, Janet Rich-Edwards, Jordan W Smoller, Rosalind J Wright and Shaun M Purcell
    Citation: BMC Psychiatry 2009 9:29
  26. Topiramate might be effective in the treatment of posttraumatic stress disorder (PTSD) because of its antikindling effect and its action in both inhibitory and excitatory neurotransmitters. Open-label studies ...

    Authors: Marcelo Feijó Mello, Mary Sau Ling Yeh, Jair Barbosa Neto, Luciana Lorens Braga, Jose Paulo Fiks, Daniela Deise Mendes, Tais S Moriyama, Nina Leão Marques Valente, Mariana Caddrobi Pupo Costa, Patricia Mattos, Rodrigo Affonseca Bressan, Sergio Baxter Andreoli and Jair Jesus Mari
    Citation: BMC Psychiatry 2009 9:28
  27. Filicide, the killing of one's child, is an extraordinary form of homicide. It has commonly been associated with suicide and parental psychiatric illness. In the research on filicide, nationwide studies with c...

    Authors: Hanna Putkonen, Ghitta Weizmann-Henelius, Nina Lindberg, Markku Eronen and Helinä Häkkänen
    Citation: BMC Psychiatry 2009 9:27
  28. Because a large proportion of patients with panic attacks receiving approved pharmacotherapy do not respond or respond poorly to medication, it is important to identify additional therapeutic strategies for th...

    Authors: James M Prosser, Samantha Yard, Annie Steele, Lisa J Cohen and Igor I Galynker
    Citation: BMC Psychiatry 2009 9:25
  29. Surveys on prescription patterns for antipsychotics in the Scandinavian public health system are scarce despite the prevalent use of these drugs. The clinical differences between antipsychotic drugs are mainly...

    Authors: Rune A Kroken, Erik Johnsen, Torleif Ruud, Tore Wentzel-Larsen and Hugo A Jørgensen
    Citation: BMC Psychiatry 2009 9:24
  30. Since the late 1980s, the Lord's Resistance Army (LRA), a spiritualist rebel group in northern Uganda, has killed and mutilated thousands of civilians and abducted an estimated 52,000 to 75,000 people to serve...

    Authors: Phuong N Pham, Patrick Vinck and Eric Stover
    Citation: BMC Psychiatry 2009 9:23
  31. The North-Eastern part of Sri Lanka had already been affected by civil war when the 2004 Tsunami wave hit the region, leading to high rates of posttraumatic stress disorder (PTSD) in children. In the acute aft...

    Authors: Claudia Catani, Mahendran Kohiladevy, Martina Ruf, Elisabeth Schauer, Thomas Elbert and Frank Neuner
    Citation: BMC Psychiatry 2009 9:22
  32. Most epidemiologic studies concerned with Major Depressive Disorder have employed cross-sectional study designs. Assessment of lifetime prevalence in such studies depends on recall of past depressive episodes....

    Authors: Scott B Patten
    Citation: BMC Psychiatry 2009 9:19
  33. The aim of the study was to evaluate psychopathy-like personality traits in a nationwide consecutive sample of adolescent male homicide offenders and to compare the findings with those of a randomly sampled ad...

    Authors: Nina Lindberg, Taina Laajasalo, Matti Holi, Hanna Putkonen, Ghitta Weizmann-Henelius and Helinä Häkkänen-Nyholm
    Citation: BMC Psychiatry 2009 9:18
  34. Schizophrenia is likely to be a consequence of DNA alterations that, together with environmental factors, will lead to protein expression differences and the ultimate establishment of the illness. The superior...

    Authors: Daniel Martins-de-Souza, Wagner F Gattaz, Andrea Schmitt, José C Novello, Sérgio Marangoni, Christoph W Turck and Emmanuel Dias-Neto
    Citation: BMC Psychiatry 2009 9:17
  35. It has been suggested that dopamine dysfunction may play a role in bipolar disorder (BD). An indirect approach to examine this issue was developed, focusing on associations between dopamine proxy measures obse...

    Authors: Inge van Rossum, Diederik Tenback and Jim van Os
    Citation: BMC Psychiatry 2009 9:16
  36. Attention Deficit/Hyperactivity Disorder (ADHD) is a neurobehavioural disorder, affecting 3–6% of school age children and adolescents in Spain. Methylphenidate (MPH), a mild stimulant, had long been the only a...

    Authors: Jihyung Hong, Tatiana Dilla and Jorge Arellano
    Citation: BMC Psychiatry 2009 9:15
  37. This correction reports changes in our protocol since its publication. These include changes to authorship and acknowledgements, together with improvements to study design and procedures, and correction of an ...

    Authors: Seren Haf Roberts, Emma Bedson, Dyfrig A Hughes, Keith R Lloyd, David B Menkes, Stuart J Moat, Munir Pirmohamed, Gary P Slegg, Johannes Thome, Richard Tranter, Rhiannon Whitaker, Clare Wilkinson and Ian T Russell
    Citation: BMC Psychiatry 2009 9:14

    The original article was published in BMC Psychiatry 2007 7:65

  38. How long an antipsychotic is effective in maintaining response is important in choosing the correct treatment for people with schizophrenia. This post-hoc analysis describes maintenance of response over 24 or ...

    Authors: Virginia Stauffer, Haya Ascher-Svanum, Lin Liu, Tamara Ball and Robert Conley
    Citation: BMC Psychiatry 2009 9:13
  39. This study focuses on exploring the relationship between changes in appetite or eating behaviors and subsequent weight change for adult patients with schizophrenia or bipolar disorder treated with olanzapine a...

    Authors: Virginia L Stauffer, Ilya Lipkovich, Vicki Poole Hoffmann, Alexandra N Heinloth, H Scott McGregor and Bruce J Kinon
    Citation: BMC Psychiatry 2009 9:12
  40. we know very little about mental health practitioners' views on treatments to change sexual orientation. Our aim was to survey a representative sample of professional members of the main United Kingdom psychot...

    Authors: Annie Bartlett, Glenn Smith and Michael King
    Citation: BMC Psychiatry 2009 9:11
  41. Clinician training deficits and a low and declining autopsy rate adversely impact the quality of death certificates in the United States. Self-report and records data for the general population indicate that p...

    Authors: Ian RH Rockett, Yinjuan Lian, Steven Stack, Alan M Ducatman and Shuhui Wang
    Citation: BMC Psychiatry 2009 9:10
  42. The Psychiatric arm of the population-based CoLaus study (PsyCoLaus) is designed to: 1) establish the prevalence of threshold and subthreshold psychiatric syndromes in the 35 to 66 year-old population of the c...

    Authors: Martin Preisig, Gérard Waeber, Peter Vollenweider, Pascal Bovet, Stéphane Rothen, Caroline Vandeleur, Patrice Guex, Lefkos Middleton, Dawn Waterworth, Vincent Mooser, Federica Tozzi and Pierandrea Muglia
    Citation: BMC Psychiatry 2009 9:9
  43. Inhalant use is among the most pernicious and poorly understood forms of adolescent substance use. Many youth in the juvenile justice system have used inhalants, but little is known about inhalant use disorder...

    Authors: Matthew O Howard and Brian E Perron
    Citation: BMC Psychiatry 2009 9:8

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