The co-morbidity of DSM-V Gambling with DSM-V mental disorders and substance abuse in a Kenyan context of high risk schizophrenia
BMC Psychiatry volume 23, Article number: 239 (2023)
There is evidence that gambling disorder shares similarities with other types of addictive behavior, such as occurs in substance abuse. In addition, co-morbidity of gambling with mental disorders has been established in school-going students.
This study aimed at determining the comorbidity of DSM-V gambling disorder with DSM-V mental disorders and substance abuse in high school, college and university students in Kenya.
This was a cross-sectional study among 536 high school, college and university students. We collected data on socio-demographic characteristics, economic indicators, DSM-V diagnosis including DSM-V gambling disorder and substance use disorders using the WHO ASSIST tool. Descriptive and inferential analyses were done.
A total of 536 students participated in the study, of which 11.4% (61 out of 536) had DSM-V gambling disorder. Male gender (AOR = 12.0, 95% CI: 4.99–34.3), antisocial personality disorder (AOR = 3.42, 95% CI: 1.34–8.54), tobacco use (AOR = 4.42, 95% CI: 1.15–18.3) and conduct disorder (AOR = 7.56, 95% CI: 2.34–25.1) were predictors of gambling disorder.
Gambling is highly prevalent in Kenya learning institutions at 11.4% and is associated with mental disorders and substance use. There is a need for public awareness of gambling among Kenyan youths.
The DSM-IV pathological gambling disorder has been re-classified as an addictive disorder in DSM V based on evidence that it has addictive characteristics and shares similarities with other types of addictive behavior, such as occurs in substance abuse .
The prevalence of pathological gambling in population studies in High Income Countries (HICs) ranges from 0.4% to 2.0% in the USA and Canada , 5.7% lifetime gambling in Sweden  and 30% lifetime gambling in a USA based school study . High prevalence rates have been reported in South Africa, Nigeria and Ethiopia ranging between 3.2% and 28.3% in the 12–28 age group . A more recent report has suggested that 54% of the youth in sub-Sahara Africa gambled, [6, 7], with the highest lifetime gambling at 76% being reported in Kenya [6, 7]. Up to 78% of University students are engaged in gambling which is more than the general population . On co-morbidity, Kessler et al. 2008 reported co-morbidity of gambling with mental disorders mainly depression, while a Swedish study reported co-morbidity with cigarette and marijuana in school going students . Media reports have suggested that gambling is related to suicide in Kenya, Uganda and Tanzania . The significance of gambling even on a global scale is underlined by the involving access to online gambling fuelled by the aggressive marketing of betting companies .
An important shortcoming of these Kenya and most reports from Africa are that they are not based on clear diagnostic criteria of associated mental disorders and substance use and clearly defined socio-demographic factors and economic indicators. The objective of this study is to fill the above gaps in Africa in general and Kenya in particular on Kenyan youths attending school, college and university who had been identified as at high risk of developing schizophrenia .
The primary aims are: -
To determine the prevalence of DSM-V gambling disorder in the study population.
To determine the co-morbidity of gambling disorder with DSM-V mental disorders.
To determine the co-morbidity of gambling disorder with WHO’s Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST) alcohol and substance use disorders.
To determine the predictors of gambling disorder.
Secondary aims are:
To determine the patterns of the various DSM-V symptoms of gambling disorder.
To determine the varying severity of gambling.
To determine if gambling disorder as an addictive disorder, co-exists with substance and alcohol dependency.
The study participants
This cross-sectional study was leveraged in a study of 536 students from high schools, colleges and universities who met the criteria of being at risk for schizophrenia using the Washington Early Recognition Center Affectivity and Psychosis (WERCAP). The students had been identified from 9,742 high school, college and university students. The details of this student population and how they were recruited have been described in several publications [11, 12].
Permission was sought from institutional heads for the tertiary academic institutions, and from the local community administration for high school participants. Inclusion criteria were the ability to read, write and speak English and informed and signed voluntary assent and consent forms. Informed consent was obtained for those over 18 years. For those under 18 years, we obtained consent from the parents/guardians and also assent from the students.
Tools and measurements
A researcher-designed socio-demographic questionnaire was used to capture age, gender, the highest level of education, marital status and birth order.
Economic indicators tool
It records household items that are used to estimate economic status by the creation of a wealth index . The wealth index used is based on the World Bank recommendation for Low Middle-Income Countries (LMICs)  and has been adopted by the Kenya Government for use in Kenya. It is classified into five sections; quintiles 1–5 with quintile 1 representing the lowest level of wealth and 5 the highest level.
The Diagnostic Interview Schedule (DIS) tool for DSM-V diagnosis
The DIS is an online tool that has questions that are read to research participants by a trained research assistant who scores the responses and an algorithm that generates DSM-V diagnoses . Even as we chose this tool, which have been extensively used, we were aware of the dialogue on the validity. On the one hand, it has been argued that tools such as the DIS, may provide statistical over- estimates because they leave out important information about clients' personal history, personality style, and other contextual variables while on the other hand there is evidence that it has good diagnostic value [12, 15].
Drug and substance
The WHO’s ASSIST  was used only to determine the prevalence of different types of substance use on a ‘Yes’ or ‘No’ dimension. The WHO ASSIST has been used in Kenya  and other countries in Africa .
Training on data collection
This was done by one of us (DM from Washington University, St. Louis) on a face to face residential training in Kenya assisted by four researchers (a psychiatrist, public health physician, clinical psychologist and graduate nurse), who were trained on the administration of the DIS at the University of Florida by the developers of the DIS. These acted as trainers of trainees of the research assistants in Kenya.
Data collection was overseen by DMN & VM from Africa Mental Health Research and Training Foundation (AMHRTF). The lead research assistant was a university Master Level graduate nurse who was responsible for the supervision of all sites and all data collection and transmission to AMHRTF headquarters. He supervised informed consent and sat through all data collection sessions.
Data management and analysis
Data were checked, cleaned and exported to Statistical Package for the Social Sciences (SPSS) for analysis. All data analyses were performed with SPSS version 21 (IBM, Chicago, IL). Basic descriptive statistics presented in the form of frequency and percentages were done. Chi-square tests were used for categorical data to analyze the difference in gambling disorder proportion across socio-demographics, mental disorders and substance use variables. The strength and significance of the association between the variables and gambling disorder was assessed with a 95% confidence level. Variables with a p-value less than 0.05 were then fitted into logistic regression models to identify the predictors of gambling disorder. Multivariate binomial logistic regression was employed to identify the determinants while univariate ordinal logistic regression was employed to identify the association between suicidality and severity of gambling disorder. Correlation analysis was also carried out between gambling disorder and mental disorders and substance use. Statistical significance was considered at a p-value < 0.05.
Ethical approval was granted by the Maseno University Ethics Review Board in Kenya (IRB number MSU/DRPI/MUERC/00344/16).
This being the first study of its kind, we presented as much data as possible through tables and figures for the readers and for purposes of data sharing.
Severity of gambling disorder and prevalence of the symptoms
Out of 536 study participants, 11.4% (61 out of 536) had DSM V gambling disorder. There was a decreasing severity of the gambling disorder (5.2%, 4.6% and 1.7%) from mild, moderate to severe and also decreasing frequency of different types of gambling symptoms. Non-disordered gamblers comprised of 88.6% (Figs. 1 and 2).
Gambling and socio-demographics
Of the socio-demographic variables studied, male gender was the only significant factor associated with gambling (< 0.05) as summarized in Table 1. The other nine variables were not significantly associated with gambling.
Gambling and mental disorders
The DSM-V diagnoses associated (p < 0.05) with gambling included Obsessive–Compulsive Disorder (OCD), psychosis, agoraphobia, social phobia, drug abuse and alcohol dependence, antisocial personality disorder, conduct and oppositional defiant disorders. The WERCAP schizophrenia was also associated with gambling (Table 2).
Gambling and substance use
Gambling was associated (p < 0.05) with all substances lifetime use except for amphetamine lifetime and inhalants lifetime use and with all substances current use except for amphetamine, hallucinogens and khat (a psych-stimulant herb) (Table 3).
The independent predictors of gambling (p < 0.05) were male gender, antisocial personality behavior, tobacco lifetime use, WERCAP schizophrenia and conduct disorders (Table 4).
Gambling and suicidality
Table 5 summarizes the association between gambling disorder and suicide. We found significant association between severity of gambling and suicidality.
Correlation between gambling and DSM V/ Substance use disorders
As far as we were able to determine from the literature on global and African studies, we present the first study reported in Africa and Kenya in particular that examines a wide range of factors associated with gambling disorder in youth aged 15–25 and attending educational institutions (high school, college and university). We describe the prevalence of DSM-V gambling disorder, the severity of the gambling disorder, patterns of individual symptoms of gambling, associated socio-demographic and economic indicators and co-morbidity with DSM-V disorders, WHO ASSIST substance abuse disorders and suicidality (ideas and behavior). This combination of multiple study variables serves to inform a more inclusive intervention.
The prevalence of 11.4% of DSM-V gambling disorder found in this study is far less than the 54–76% reported so far in Kenya, Uganda and Africa in general and also less than the 30% reported in USA schools. The explanation for this disparity of finding is mainly on the methodology we used – i.e. clear diagnostic criteria as opposed to media reports – in Kenya. This is in spite of the fact that this study was on students at risk of developing schizophrenia, though not yet developed schizophrenia. Of this 11.4%, the gambling disorder comes in various degrees of severity. It is noteworthy that of the DSM-V symptoms of gambling disorder, the leading 4 symptoms in prevalence (Q6, Q4, Q1, Q3) in the descending order are addiction behaviors, providing Kenyan evidence in support for re-classifying gambling as an addiction disorder amongst other drug addiction disorders. Also of note is that students identified money as a driving factor (Q1, Q6, Q9) even though there was no significant association between gambling and economic indicators (employment status of the guardian/parents and the wealth index). This would suggest a directional cause from addictive gambling to money concerns to sustain the addiction. The students did not associate gambling with any lost educational opportunities or loss of social relationships with only 0.7% scoring positive for the symptoms.
Male gender was the only socio-demographic variable significantly associated with gambling. Anti-social personality disorder, conduct disorder and oppositional disorder, all significantly (p < 0.05) associated with gambling (Table 3) are disorders that are largely associated with the male gender and therefore not surprising that the male gender was the only socio demographic factor that was associated with gambling. It is noteworthy that there was no difference in age structure suggesting that gambling occurs equally across the ages. This is not surprising given that advertising of gambling through radio/television and social media and given the almost-universal access to mobile phones, all age groups are equally targeted. All these suggest that gambling is primarily a learned behavior through advertisement with "promises" of huge gains in money, reinforced from time to time by occasional money gains.
It is noteworthy that gambling was not associated with major depression (p > 0.05). The psychiatric disorders significantly (p < 0.05) associated with gambling were agoraphobia and social phobia which are more indicative of social disconnect rather than social connect and so are the personality disorders (anti-social, conduct and oppositional defiant), DSM-V psychosis and WERCAP schizophrenia suggesting that gambling is not a sign of shared group activity but individual driven activity.
Being an addiction disorder as per its leading scores on DSM-V symptoms, it is not surprising that gambling disorder is co-morbid with both lifetime and current use of most of the WHO-ASSIST listed drugs of abuse. The significant association of OCD and alcohol abuse/dependence and drug abuse is not unexpected, given that they share symptoms of repeated behaviors.
The two different models used to predict gambling produced similar results, confirming the validity of the predictors. These predictors include male gender, antisocial personality and conduct disorders, high risk factors for psychosis and tobacco both lifetime and current. Apart from high risk WERCAP for schizophrenia, no particular mental disorder was a predictor of gambling.
Our findings provide an evidence base for the need for (i) enhanced public awareness on the prevalence of gambling and its association with mental disorders, substance use and high levels of suicidality in Kenya learning institutions; (ii) screening for mental, alcohol and substance use and suicidality in cases of gambling; (iii) controlled advertisement of gambling and (iv) gambling to be viewed indeed as an addiction disorder.
Gambling is highly prevalent in Kenya learning institutions at 11.4% though still less than previously reported in media reports
It occurs in equal prevalence in the age group 15–19 (found in schools) and 20–25 (found in college and university levels)
Gambling is associated with mental disorders – namely agoraphobia, social phobia, psychosis and suicidality
Gambling is associated with most substance of abuse
There is a need for public awareness, control of advertisement and access to gambling apps for the Kenyan youths
Gambling needs a broad-based public and clinical approach.
Limitations and strength
This study consisted of a subset of 536 study participants who had scored positive for high risk psychosis (not yet converted), thus the high rates of DSM-V psychosis in our findings (51.1%) and the high rate of various degrees of WERCAP psychosis. However, apart from the psychosis which we have explained, our data provide information on other associations of gambling disorder that may be useful for a clinical and public awareness campaign.
As already mentioned in the methodology, there have been arguments for and against the use of DIS as a valid tool. We do not know how precisely these different arguments may have affected our results. But we lean on the strengths that we had already validated WERCAP in our socio-cultural setting.
A major strength of this study is that for all the diagnoses we used well defined DSM-V criteria for DSM-V diagnoses and WHO ASSIST for alcohol and various substance use.
Availability of data and materials
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
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All the participants who participated in the study and the different institutions and communities who facilitated the study, Africa Mental Health Research and Training Foundation for facilitating the study.
All the guidelines have been followed and adhered to as per the journal requirements.
Africa Mental Health Research and Training Foundation (AMHRTF) in-house support for this particular set of data collection and analysis. The Foundation did not influence researchers, since they work independently.
Ethics approval and consent to participate
Ethical approval was granted by the Maseno University Ethics Review Board in Kenya (IRB number MSU/DRPI/MUERC/00344/16). All methods were performed in accordance with relevant guidelines and regulations as per the World Medical Association Declaration of Helsinki – ethical principles for medical research involving human subjects. Informed consent was obtained from participants aged 18 + and from parents of participants who were below the age of 18. Participants below 18 years signed assent forms.
Consent for publication
The authors declare no competing interests.
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Correlation between Gambling and DSM V disorders. Supplementary Table S2. Correlation between Gambling and lifetime substance use. Supplementary Table S3. Correlation between Gambling and current substance use.
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Cite this article
Ndetei, D.M., Mutiso, V., Momanyi, R. et al. The co-morbidity of DSM-V Gambling with DSM-V mental disorders and substance abuse in a Kenyan context of high risk schizophrenia. BMC Psychiatry 23, 239 (2023). https://doi.org/10.1186/s12888-023-04738-4
- Mental disorders
- Substance use
- Kenyan context